Methyl 4-bromo-3-sulfamoylbenzoate CAS 74451-73-3
| CAS No. | 74451-73-3 |
| Molecular Formula | C8H8BrNO4S |
| Molecular Weight | 294.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 294.12 g/mol gives Methyl 4-bromo-3-sulfamoylbenzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 4-bromo-3-sulfamoylbenzoate (CAS 74451-73-3), a certified reference material (molecular formula C8H8BrNO4S, MW 294.12 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 4-bromo-3-sulfamoylbenzoate (C8H8BrNO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8BrNO4S |
| Molecular Weight | 294.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 5-BRomo-2-fluoro-n-phenylbenzamide (CAS 1016847-17-8)
- Methyl 4-bromo-2-sulfamoylbenzoate (CAS 1202366-59-3)
- 5-Bromo-2-(methylsulfonamido)benzoic Acid (CAS 1225713-29-0)
- 7-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide (CAS 1342745-35-0)
- Methyl 3-bromo-5-sulfamoylbenzoate (CAS 1343983-13-0)
- 1-Bromo-2-(ethylsulfonyl)-4-nitrobenzene (CAS 1375472-10-8)
- 5-Bromo-2-methyl-3-sulfamoylbenzoic acid (CAS 1375472-31-3)
- 3-Bromo-2-methyl-5-sulfamoylbenzoic acid (CAS 1489091-39-5)
Recommended Standards
- Methyl 3-bromo-4-sulfamoylbenzoate (CAS 89978-60-9)
- N-(2-Bromophenyl)-2-fluorobenzamide (CAS 349612-20-0)
- Methyl 2-Bromo-5-sulfamoylbenzoate (CAS 924867-88-9)
- N-(2-Bromophenyl)-4-fluorobenzamide (CAS 671-13-6)
- 6-(sec-Butoxy)-2-((4-methoxyphenyl)thio)pyrimidin-4(3H)-one (CAS 284681-76-1)
- ((1R,2R)-2-(trifluoromethyl)cyclobutyl)methanamine hydrochloride (CAS 2460740-25-2)
- methyl 2-methyl-4H-pyrrolo[3,2-d]thiazole-5-carboxylate (CAS 238749-56-9)
- 3-Bromo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine (CAS 1263378-90-0)
- 1,3-Dimethyl-1H-thieno[2,3-c]pyrazole (CAS 50734-86-6)
- 1-(4-ethoxyphenyl)hexahydropyrimidine-2,4-dione (CAS 19144-78-6)
- 2-(2-Bromoethoxy)-1-chloro-3-methylbenzene (CAS 26646-29-7)
- ((1R,2R)-2-(2-Ethylbenzo[d]oxazol-7-yl)cyclopropyl)methanol (CAS 625851-01-6)
- 2-chloro-5-methoxybenzenesulfonamide (CAS 502187-53-3)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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