N-[(Dimethylamino)methylene]-N-[3-(trifluoromethyl)phenyl]thiourea CAS 74466-87-8
| CAS No. | 74466-87-8 |
| Molecular Formula | C11H12F3N3S |
| Molecular Weight | 275.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, N-[(Dimethylamino)methylene]-N-[3-(trifluoromethyl)phenyl]thiourea is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 275.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies N-[(Dimethylamino)methylene]-N-[3-(trifluoromethyl)phenyl]thiourea (CAS 74466-87-8), a certified reference material (molecular formula C11H12F3N3S, MW 275.29 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-[(Dimethylamino)methylene]-N-[3-(trifluoromethyl)phenyl]thiourea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F3N3S |
| Molecular Weight | 275.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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- 3-(Benzyloxy)benzamide (CAS 171861-74-8)
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- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
Why CATO?
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