1-(2-Hydroxy-3-methoxy-5-methylphenyl)ethanone CAS 7452-85-9
| CAS No. | 7452-85-9 |
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(2-Hydroxy-3-methoxy-5-methylphenyl)ethanone (CAS 7452-85-9) is a high-purity analytical reference standard with the molecular formula C10H12O3 and a molecular weight of 180.20 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, 1-(2-Hydroxy-3-methoxy-5-methylphenyl)ethanone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 180.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Hydroxy Standards
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- 4-Hydroxy-3-propoxybenzaldehyde (CAS 110943-74-3)
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- Ethyl 3-hydroxy-5-methylbenzoate (CAS 1126430-75-8)
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Recommended Standards
- 1-(2-Ethoxy-6-hydroxyphenyl)ethan-1-one (CAS 2750-25-6)
- 1-(2-Hydroxy-3-methoxyphenyl)propan-2-one (CAS 205826-72-8)
- 1-(2,4-Dihydroxyphenyl)-2-methylpropan-1-one (CAS 29048-54-2)
- 1-(2-Hydroxy-4-methoxy-3-methylphenyl)ethanone (CAS 69469-91-6)
- 2-Amino-4-methylbenzoxazole (CAS 947504-99-6)
- 2,2,2-Trifluoro-N-(2-(prop-1-en-2-yl)phenethyl)acetamide (CAS 2632991-49-0)
- 11B-benzyl-9-hydroxy-5,6,7,11b-tetrahydro-1H-dibenzo[a,c][7]annulen-3(2H)-one (CAS 1400924-57-3)
- (3S)-2,4,5-Trifluoro-3-hydroxybenzenebutanoic acid (CAS 868071-17-4)
- Finerenone Impurity 55 (CAS CATO-C4X-288055)
- 4-(6-Hydroxy-3-methylbenzofuran-2-yl)benzene-1,3-diol (CAS 61135-96-4)
- 2-Ethylphenothiazine (CAS 61852-27-5)
- 1-(1,3-Dimethyl-5-phenyl-1H-pyrazol-4-yl)ethanone (CAS 77435-41-7)
- 2-(4-Chloro-Benzyl)-malonic acid diethyl ester (CAS 37556-13-1)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
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