2-(3,4-Dichlorophenyl)-3-methylbutanoic acid CAS 74569-33-8
| CAS No. | 74569-33-8 |
| Molecular Formula | C11H12Cl2O2 |
| Molecular Weight | 247.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3,4-Dichlorophenyl)-3-methylbutanoic acid (CAS 74569-33-8), molecular formula C11H12Cl2O2 and molecular weight 247.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(3,4-Dichlorophenyl)-3-methylbutanoic acid (C11H12Cl2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3,4-Dichlorophenyl)-3-methylbutanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12Cl2O2 |
| Molecular Weight | 247.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
Related Dichlorophenyl Standards
- 3-(2,4-Dichlorophenyl)-3-methylbutanoic acid (CAS 1225858-77-4)
- 3-(3,4-Dichlorophenyl)-2,2-dimethylpropanoic acid (CAS 1226172-50-4)
- 2-(2,3-Dichlorophenyl)-3-methylbutanoic acid (CAS 1247394-50-8)
- methyl 4-(3,4-dichlorophenyl)butanoate (CAS 1368308-27-3)
- 3-(2,5-Dichlorophenyl)-3-methylbutanoic acid (CAS 1506268-17-2)
- 2-(2,4-Dichlorophenyl)-3-methylbutanoic acid (CAS 83340-81-2)
- 5-(3,4-Dichlorophenyl)pentanoic acid (CAS 34658-33-8)
- Ethyl 3-(2,4-dichlorophenyl)propanoate (CAS 69793-07-3)
Recommended Standards
- 2-(4-Chloro-3-methylphenoxy)butanoyl chloride (CAS 86464-91-7)
- 1,4-Dichloroanthracene (CAS 66259-12-9)
- 2,3-Dichloroanthracene (CAS 613-07-0)
- 1,2-Bis(3-chlorophenyl)ethyne (CAS 5216-30-8)
- 2-(5-Cyclopropyl-1-methyl-1H-pyrazol-3-yl)-2-hydroxyacetic acid (CAS 2413995-58-9)
- 2,9-Dichloro-1-nonene (CAS 485320-14-7)
- 3,5-Dimethyl-4-(morpholinosulfonyl)phenol (CAS 1704067-04-8)
- (5α,17β)-N-Methoxy-N-methyl-3-oxo-4-azaandrost-1-ene-17-carboxamide (CAS 138689-15-3)
- 1-(4,6-Bis(trifluoromethyl)pyridin-2-yl)ethan-1-one (CAS 1393554-55-6)
- 3-(4-(Difluoromethoxy)phenyl)-2-mercaptoquinazolin-4(3h)-one (CAS 380340-06-7)
- 5-Fluoro-2-(2-hydroxy-1-(methylamino)ethyl)phenol (CAS 1337786-64-7)
- Benzyl 2-Acetamido-3,6-di-O-benzoyl-2-deoxy-α-D-galactopyranoside (CAS 141019-70-7)
- 4-(Difluoromethyl)-5-methyl-2-(trifluoromethyl)pyridine (CAS 1805279-46-2)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com