Ethyl 4-acetyl-3-methyl-5-(methylsulfanyl)-2-thiophenecarboxylate CAS 74597-79-8

Purity 97%+In StockPharmaceutical Standards
CAS No.74597-79-8
Molecular FormulaC11H14O3S2
Molecular Weight258.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 4-acetyl-3-methyl-5-(methylsulfanyl)-2-thiophenecarboxylate CAS 74597-79-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Ethyl 4-acetyl-3-methyl-5-(methylsulfanyl)-2-thiophenecarboxylate (CAS 74597-79-8), molecular formula C11H14O3S2 and molecular weight 258.36 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Ethyl 4-acetyl-3-methyl-5-(methylsulfanyl)-2-thiophenecarboxylate (C11H14O3S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), Ethyl 4-acetyl-3-methyl-5-(methylsulfanyl)-2-thiophenecarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H14O3S2
Molecular Weight258.36 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1978
Sulfur Atoms2

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