2-Amino-5-bromo-6-(4-fluorophenyl)pyrimidin-4(3H)-one CAS 74602-62-3
| CAS No. | 74602-62-3 |
| Molecular Formula | C10H7BrFN3O |
| Molecular Weight | 284.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Amino-5-bromo-6-(4-fluorophenyl)pyrimidin-4(3H)-one (CAS 74602-62-3) is a high-purity analytical reference standard with the molecular formula C10H7BrFN3O and a molecular weight of 284.08 g/mol.
2-Amino-5-bromo-6-(4-fluorophenyl)pyrimidin-4(3H)-one (C10H7BrFN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7BrFN3O |
| Molecular Weight | 284.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 4-Amino-5-bromo-1-(3-fluorophenyl)pyrimidin-2(1H)-one (CAS 1416439-25-2)
- 2-Amino-5-bromo-6-(2-fluorophenyl)pyrimidin-4(3H)-one (CAS 74602-56-5)
- 2-Amino-5-bromo-6-(3-fluorophenyl)pyrimidin-4(3H)-one (CAS 74602-59-8)
- 5-Amino-4-bromo-2-(4-fluorophenyl)pyridazin-3(2H)-one (CAS 52391-95-4)
- (s)-2-Amino-2-(3-bromo-5-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1213540-93-2)
- (r)-2-Amino-2-(3-bromo-5-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1213583-67-5)
- (r)-2-Amino-2-(2-bromo-5-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1213874-50-0)
- Methyl 2-amino-5-iodothiazole-4-carboxylate (CAS 1235034-76-0)
Recommended Standards
- 3-[(4-fluorophenyl)-5-(2-bromoacetyl)]isoxazole (CAS 888723-43-1)
- 3-Bromo-2-methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 934063-79-3)
- Methyl 5-bromo-4-sulfamoylfuran-2-carboxylate (CAS 1494621-26-9)
- 5-Bromo-8-fluoro-6-methylquinoline-2-carboxylic acid (CAS 1420794-38-2)
- (Z)-{2-[(4-chlorophenyl)sulfanyl]-1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene}[(3-methylphenyl)methoxy]amine (CAS 478047-80-2)
- 2,3-Dihydroxysuccinaldehyde (CAS 34361-91-6)
- 5-(3-Ethoxy-4-hydroxyphenyl)-4-(3-fluoro-4-methylbenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 618075-77-7)
- Ethyl 2-(pyrrolidin-2-yl)acetate hydrochloride (CAS 1251923-73-5)
- (2S,4S)-4-methylazetidine-2-carboxylic acid (CAS 1932627-43-4)
- 4-Amino-N-cyclobutylbutanamide (CAS 1249667-46-6)
- 3,6-Dibromo-1H-pyrrolo[3,2-b]pyridine (CAS 1190312-18-5)
- 1-(3,5-Difluoro-4-(isopentyloxy)phenyl)ethan-1-ol (CAS 1443345-67-2)
- 4-Bromo-3-chloro-1-methylpyridin-2(1H)-one (CAS 2172654-58-7)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
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