2-methoxy-4-nitrobenzene-1-sulfonamide CAS 746630-16-0
| CAS No. | 746630-16-0 |
| Molecular Formula | C7H8N2O5S |
| Molecular Weight | 232.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-methoxy-4-nitrobenzene-1-sulfonamide (CAS 746630-16-0), molecular formula C7H8N2O5S and molecular weight 232.21 g/mol, is a CATO reference standard with documented purity and traceability.
2-methoxy-4-nitrobenzene-1-sulfonamide (C7H8N2O5S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O5S |
| Molecular Weight | 232.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related methoxy Standards
- N-Methoxy-2-nitrobenzenesulfonamide (CAS 1061696-67-0)
- 2-Methoxy-3-nitrobenzene-1-sulfonamide (CAS 1261827-86-4)
- 2-Methoxy-5-nitrobenzenesulfonamide (CAS 82020-46-0)
- 3-Methoxy-4-nitrobenzene-1-sulfonamide (CAS 22117-82-4)
- 4-Methoxy-2-nitrobenzene-1-sulfonamide (CAS 81792-84-9)
- 4-Methoxy-3-nitrobenzene-1-sulfonamide (CAS 22939-93-1)
- 5-methoxy-2-nitrobenzene-1-sulfonamide (CAS 6451-49-6)
- N-methoxy-3-nitrobenzene-1-sulfonamide (CAS 304912-75-2)
Recommended Standards
- 2-Fluoro-N-(2-nitrophenyl)aniline (CAS 28898-02-4)
- 2-[4-(2-Fluorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetonitrile (CAS 860784-78-7)
- 2-Nitrophenol-4-sulfomethylamide (CAS 96-58-2)
- 2-[(3-fluorophenyl)amino]pyridine-3-carboxylic acid (CAS 57978-55-9)
- 2-[4-(Trifluoromethoxy)phenyl]cyclopropan-1-amine (CAS 1001316-74-0)
- 1-(2-Ethylphenyl)-1H-pyrrole-2-carbaldehyde (CAS 383135-96-4)
- 2,5-Dichloro-3-methylaniline (CAS 1379291-18-5)
- p-Hydroxy Benzphetamine (1.0mg/ml in Acetonitrile) (CAS 87182-32-9)
- 3-(((4-Fluorophenyl)sulfonyl)methyl)-5-methylisoxazole (CAS 1211292-75-9)
- 3-Methyl-N-pentyl-1-propyl-1H-pyrazol-4-amine hydrochloride (CAS 1856085-93-2)
- 2,2-Dimethyl-2,3-dihydrobenzofuran-7-yl vinylcarbamate (CAS 88309-98-2)
- 4-(piperidin-4-yl)-4H-1,2,4-triazol-3-amine dihydrochloride (CAS 1803571-60-9)
- 3-Amino-N-ethyl-N-phenylbenzamide (CAS 875837-45-9)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
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