(3-Chlorophenyl)(3,5-difluorophenyl)methanone CAS 746651-98-9
| CAS No. | 746651-98-9 |
| Molecular Formula | C13H7ClF2O |
| Molecular Weight | 252.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(3-Chlorophenyl)(3,5-difluorophenyl)methanone (CAS 746651-98-9) is a high-purity analytical reference standard with the molecular formula C13H7ClF2O and a molecular weight of 252.64 g/mol.
Structurally, (3-Chlorophenyl)(3,5-difluorophenyl)methanone (C13H7ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 252.64 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), (3-Chlorophenyl)(3,5-difluorophenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H7ClF2O |
| Molecular Weight | 252.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- (2-chlorophenyl)(2,5-difluorophenyl)methanone (CAS 1152708-07-0)
- (3-Chlorophenyl)(3,4-difluorophenyl)methanone (CAS 844884-94-2)
- (4-Chlorophenyl)(3,4-difluorophenyl)methanone (CAS 844885-01-4)
- 2-[1-(3-chlorophenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetic acid (CAS 1094331-77-7)
- 1-(4-Chlorophenyl)-5-methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylic acid (CAS 14058-89-0)
- Ethyl 3-(4-chlorophenyl)-1,2,4-oxadiazole-5-carboxylate (CAS 163719-69-5)
- 1-(2-Chlorophenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid (CAS 55983-86-3)
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Recommended Standards
- 2-Chloro-3',4'-difluoro-[1,1'-biphenyl]-4-carbaldehyde (CAS 1962207-81-3)
- (5-(Trifluoromethyl)tetrahydrofuran-2-yl)methanesulfonyl chloride (CAS 2126162-12-5)
- 2-(Trifluoromethyl)oxane-4-sulfonyl chloride (CAS 1874643-68-1)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)acetonitrile (CAS 306976-81-8)
- 4-(Tetrahydropyran-4-yloxy)aniline (CAS 917483-71-7)
- (2-Aminoethyl)[(furan-2-yl)methyl](propan-2-yl)amine (CAS 1181600-76-9)
- DL-Valine-d8 (CAS 203784-63-8)
- 5'-(4-Formylphenyl)-2',4',6'-trimethyl-[1,1':3',1''-terphenyl]-4,4''-dicarbaldehyde (CAS 2195343-70-3)
- Ethyl 4-cyclohexylbenzoate (CAS 959141-01-6)
- 5-(Hydroxymethyl)isoindolin-1-one (CAS 926307-97-3)
- 2-Hydrazinylaniline dihydrochloride (CAS 62595-81-7)
- n-(3-Isopropylphenyl)furan-2-carboxamide (CAS 1181093-16-2)
- 6-Fluoro-2-methylquinoline-4-thiol (CAS 15912-64-8)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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