Cortisol 21-Benzoate CAS 74669-84-4
| CAS No. | 74669-84-4 |
| Molecular Formula | C28H34O6 |
| Molecular Weight | 466.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Cortisol 21-Benzoate (CAS 74669-84-4), molecular formula C28H34O6 and molecular weight 466.57 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, a hydroxyl group, an ether linkage, Cortisol 21-Benzoate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 466.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H34O6 |
| Molecular Weight | 466.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
Related Cortisol Standards
- Cortisol 21-Sulfate (CAS 1253-43-6)
- Cortisol 21-mesylate (CAS 6677-96-9)
- Cortisol 21-beta-D-Glucuronide (CAS 7301-54-4)
- Cortisol 21-m-Maleimidobenzoate (CAS 73499-12-4)
- Cortisol-9,12,12-d3 (CAS 115699-92-8)
- Cortisol Impurity 4 (CAS 7050-24-0)
- Cortisol-1,2-d2 (CAS 1257650-73-9)
- Cortisol-1,2-d2 (CAS 79037-25-5)
Recommended Standards
- 4,6-Dichloro-1-nitroanthracene-9,10-dione (CAS 60506-83-4)
- FMoc-l-dab(octanoyl)-oh (CAS 1983858-56-5)
- 4-((3-((4-(2-(4-Hydroxyphenyl)propan-2-yl)phenoxy)methyl)benzyl)oxy)benzimidamide (CAS 204974-93-6)
- SDZ-201106 (CAS 97730-95-5)
- 3,4,5-Trifluorophenylthiourea (CAS 886763-01-5)
- 2-Amino-2-(2,4,5-trimethoxyphenyl)ethanol oxalate (CAS 1177339-41-1)
- tert-Butyl ((3-(4-fluorophenyl)-4,5-dihydroisoxazol-5-yl)methyl)carbamate (CAS 1488407-61-9)
- Difelikefalin Impurity 100 (CAS 1821319-30-5 (free base))
- Omeprazole Impurity 53 (CAS 73590-87-1)
- 2,2,2-Trichloroethanol (CAS 115-20-8)
- 4-(4-Benzyloxy-3-iodophenyl)butan-2-one (CAS 1648893-47-3)
- 2-(4-Acetylpiperazin-1-yl)pyridine-4-carbonitrile (CAS 1016809-01-0)
- Ticagrelor Hydrochloride (CAS 1465929-42-3)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com