(3E)-3-[(4-Methoxyphenyl)methylidene]piperazine-2,5-dione CAS 74720-31-3
| CAS No. | 74720-31-3 |
| Molecular Formula | C12H12N2O3 |
| Molecular Weight | 232.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3E)-3-[(4-Methoxyphenyl)methylidene]piperazine-2,5-dione.
(3E)-3-[(4-Methoxyphenyl)methylidene]piperazine-2,5-dione (CAS 74720-31-3) is a high-purity analytical reference standard with the molecular formula C12H12N2O3 and a molecular weight of 232.24 g/mol.
Structurally, (3E)-3-[(4-Methoxyphenyl)methylidene]piperazine-2,5-dione (C12H12N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 232.24 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3E)-3-[(4-Methoxyphenyl)methylidene]piperazine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O3 |
| Molecular Weight | 232.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Related E Standards
- 3-(2-Methoxyphenyl)-1-methyl-1h-pyrazole-5-carboxylic acid (CAS 1015868-53-7)
- 5-(2-Methoxyphenyl)-1-methyl-1h-pyrazole-4-carboxylic acid (CAS 1020722-82-0)
- 1-(4-Methoxyphenyl)-5-methyl-1h-pyrazole-3-carboxylic acid (CAS 1020724-35-9)
- 3-(3-Methoxyphenyl)-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1022575-47-8)
- 2-(3-Methoxyphenyl)-5-methyl-1h-imidazole-4-carboxylic acid (CAS 1048920-48-4)
- 3-(2-methoxyphenyl)-1-methyl-1H-pyrazole-4-carboxylic acid (CAS 1152511-14-2)
- 1-(3-Methoxyphenyl)-5-methyl-1h-pyrazole-3-carboxylic acid (CAS 1175929-14-2)
- 1-(2-Methoxyphenyl)-5-methyl-1H-pyrazole-3-carboxylic acid (CAS 1225539-41-2)
Recommended Standards
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- (5-Phenyl-1,3-dimethyl)barbituricacid (CAS 7391-66-4)
- (1Z)-1-(3,4-Dimethoxyphenyl)-N-(4H-1,2,4-triazol-4-yl)methanimine (CAS 59670-49-4)
- (E)-3-(2-(4-methoxybenzylidene)hydrazinyl)-4H-1,2,4-triazol-4-amine (CAS 312700-04-2)
- 2-((5-Methyl-1h-1,2,4-triazol-3-yl)thio)acetamide (CAS 337310-94-8)
- 2-Chloro-4-cyclobutoxybenzoic acid (CAS 1341286-03-0)
- tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate (CAS 1251732-64-5)
- Sunitinib Impurity 7 (CAS CATO-C4X-13337)
- tert-butyl 4-methyl-1,2,3,6-tetrahydropyridine-1-carboxylate (CAS 208245-73-2)
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- 2-Morpholinoethanesulfonic Acid (CAS 4432-31-9)
- H-D-Pro-NHEt . HCl (F-4245.0005) (CAS 1225063-04-6)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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