3,3-Bis(2-methoxyphenyl)isobenzofuran-1(3H)-one CAS 7477-27-2
| CAS No. | 7477-27-2 |
| Molecular Formula | C22H18O4 |
| Molecular Weight | 346.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,3-Bis(2-methoxyphenyl)isobenzofuran-1(3H)-one.
CATO supplies 3,3-Bis(2-methoxyphenyl)isobenzofuran-1(3H)-one (CAS 7477-27-2), a certified reference material (molecular formula C22H18O4, MW 346.38 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, 3,3-Bis(2-methoxyphenyl)isobenzofuran-1(3H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 346.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18O4 |
| Molecular Weight | 346.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Bis Standards
- 1-(1-(4-Methoxyphenyl)-5-oxopyrrolidine-3-carbonyl)piperidine-4-carboxylic acid (CAS 1010919-85-3)
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- 4-(4-Methoxyphenyl)-2,3-diphenyl-1,2,4-oxadiazolidin-5-one (CAS 62803-76-3)
- 4-(4-Methoxyphenyl)-5-oxo-2-(1H-pyrrol-1-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 339100-59-3)
- 6-(4-Methoxyphenyl)-1-[(3-methoxyphenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 337919-91-2)
- N-(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-morpholinobutanamide (CAS 89758-17-8)
- N-[(4-Methoxyphenyl)methyl]-3-(1H-pyrrol-1-yl)-1-benzofuran-2-carboxamide (CAS 865658-56-6)
- 4-(4-(4-Methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl)-1-phenyl-1H-pyrazol-5-amine (CAS 329901-27-1)
Recommended Standards
- 3-(Benzo[d][1,3]dioxol-5-ylmethylene)-5-(5,6,7,8-tetrahydronaphthalen-2-yl)furan-2(3H)-one (CAS 6267-79-4)
- 3,4-Dimethyl-5-hexen-3-ol (CAS 67760-91-2)
- 3-(Anthracen-9-yl)-5-(tert-butyl)-4-nitroisoxazole (CAS 922139-06-8)
- 3-[4-(5-hydroxypentoxy)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2619512-79-5)
- Ethyl 2-[4-chloro-5-methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl]acetate (CAS 345237-74-3)
- (E)-N1,N1,N4,N4-tetraallylbut-2-ene-1,4-diamine (CAS 955976-98-4)
- 4-Chloro-2-(4-chlorophenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine (CAS 1924486-83-8)
- 4-(((Tert-butoxycarbonyl)amino)methyl)bicyclo[2.1.1]Hexane-1-carboxylic acid (CAS 2108194-57-4)
- 3-Methyl-2,5-pyrazinediethanol (CAS 96681-84-4)
- (4-Formylphenyl)methanesulfonyl Chloride (CAS 1196151-28-6)
- Dicycloverine (CAS 77-19-0)
- Methyl cis-15-tetracosenoate (CAS 2733-88-2)
- tert-Butyl 7-hydroxy-5-azaspiro[3.4]octane-5-carboxylate (CAS 2413878-41-6)
- Vialox Peptide(Pentapeptide-3) diacetate (CAS 725232-44-0)
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