2-amino-1,3-thiazole-5-sulfonyl fluoride CAS 7478-52-6
| CAS No. | 7478-52-6 |
| Molecular Formula | C3H3FN2O2S2 |
| Molecular Weight | 182.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-amino-1,3-thiazole-5-sulfonyl fluoride (CAS 7478-52-6), molecular formula C3H3FN2O2S2 and molecular weight 182.20 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-amino-1,3-thiazole-5-sulfonyl fluoride (C3H3FN2O2S2) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 182.20 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H3FN2O2S2 |
| Molecular Weight | 182.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related amino Standards
- Methyl 3-amino-4-cyanothiophene-2-carboxylate (CAS 102123-28-4)
- 4-Amino-5H-pyrimido[4,5-b][1,4]thiazin-6(7H)-one (CAS 120267-09-6)
- 3-Amino-6-methyl-7H-thiazolo[3,2-b][1,2,4]triazin-7-one (CAS 16943-37-6)
- 2-Amino-7-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (CAS 31737-02-7)
- 4-Amino-5-(2-furyl)-4H-1,2,4-triazole-3-thiol (CAS 80809-38-7)
- Methyl 4-Amino-5-cyanothiophene-2-carboxylate (CAS 648412-51-5)
- Methyl 5-amino-4-cyanothiophene-2-carboxylate (CAS 98257-18-2)
- 2-Amino-N-(4-fluoro-2-methylphenyl)acetamide (CAS 1016507-22-4)
Recommended Standards
- 2-[(dimethylsulfamoyl)amino]acetic acid (CAS 299464-21-4)
- 2,4-Dihydroxy-5-methylthieno[2,3-d]pyrimidine (CAS 75860-79-6)
- 2-Cyanobenzenesulfonamide (CAS 73542-86-6)
- 2-(Methylthio)Pyrazolo[1,5-A][1,3,5]Triazin-4(3H)-One (CAS 54346-18-8)
- 1-[(3,5-Dimethylisoxazol-4-yl)methyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 1119452-79-7)
- [4-(Propan-2-yl)phenyl]methanethiol (CAS 4427-53-6)
- N-Methyl-4-(piperidin-1-yl)aniline (CAS 173186-18-0)
- Cl And SO42- In Water (CAS CATO-CCRM106011)
- (3-((Trifluoromethyl)thio)pyridin-2-yl)methanol (CAS 2384949-63-5)
- N-(4-Methoxybenzyl)cotinine-d (CAS 1020719-59-8)
- 1-Cyclopentylcyclohexane-1-carboxylic acid (CAS 78343-35-8)
- Apixaban Impurity 173 (CAS CATO-C4X-1088173)
- N-(2-Chloro-4-fluoro-6-methylphenyl)acetamide (CAS 1710696-26-6)
- Liraglutide Impurity 22 (CAS 536721-25-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com