1,4-Bis(4-aminophenyl)-1,4-diazacyclohexane CAS 7479-12-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,4-Bis(4-aminophenyl)-1,4-diazacyclohexane.

1,4-Bis(4-aminophenyl)-1,4-diazacyclohexane (CAS 7479-12-1), molecular formula C16H20N4 and molecular weight 268.36 g/mol, is a CATO reference standard with documented purity and traceability.

1,4-Bis(4-aminophenyl)-1,4-diazacyclohexane (C16H20N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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