2-Bromo-5-chloro-benzenesulfonamide CAS 749252-96-8
| CAS No. | 749252-96-8 |
| Molecular Formula | C6H5BrClNO2S |
| Molecular Weight | 270.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-chloro-benzenesulfonamide.
2-Bromo-5-chloro-benzenesulfonamide (CAS 749252-96-8) is a high-purity analytical reference standard with the molecular formula C6H5BrClNO2S and a molecular weight of 270.53 g/mol.
2-Bromo-5-chloro-benzenesulfonamide (C6H5BrClNO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-5-chloro-benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BrClNO2S |
| Molecular Weight | 270.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-3-chlorobenzene-1-sulfonamide (CAS 1032507-45-1)
- 5-bromo-2-chlorobenzene-1-sulfonamide (CAS 1208077-22-8)
- 2-Bromo-3-chlorobenzenesulfonamide (CAS 1261499-12-0)
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Recommended Standards
- 6-Bromo-2-methylpyridine-3-sulfonyl chloride (CAS 1596954-10-7)
- 3-Bromo-4-chlorobenzene-1-sulfonamide (CAS 900814-26-8)
- 6-Bromo-4-methylpyridine-3-sulfonyl chloride (CAS 1592629-33-8)
- 4-Bromo-2-chlorobenzenesulfonamide (CAS 351003-59-3)
- Ammonium ferrioxalate (CAS 14221-47-7)
- 2-(5-Chloro-2-nitrophenoxy)acetic acid (CAS 1250371-74-4)
- 3-(2-Methoxyphenyl)-1-[(4-methylbenzene)sulfonyl]-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 875639-17-1)
- 3-Decyloxyphenol (CAS 103147-22-4)
- Flumethasone 21-Pivalate (CAS 2002-29-1)
- 2-[(4-chlorophenyl)amino]-2-methylpropanoic acid (CAS 17413-86-4)
- Tert-butyl 3,4-dibromo-1H-indole-1-carboxylate (CAS 219943-38-1)
- Isoquinolin-1(7H)-one (CAS 734529-40-9)
- 1-(3-Bromo-2,2-dimethylpropyl)-3-methylbenzene (CAS 1493973-81-1)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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