2-(4-Chlorophenyl)indolizine CAS 7496-73-3
| CAS No. | 7496-73-3 |
| Molecular Formula | C14H10ClN |
| Molecular Weight | 227.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chlorophenyl)indolizine.
2-(4-Chlorophenyl)indolizine (CAS 7496-73-3) is a high-purity analytical reference standard with the molecular formula C14H10ClN and a molecular weight of 227.69 g/mol.
Based on its molecular formula C14H10ClN, 2-(4-Chlorophenyl)indolizine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 227.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chlorophenyl)indolizine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10ClN |
| Molecular Weight | 227.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 1-(4-Chlorophenyl)indolizine (CAS 101094-57-9)
- 2-(2-Chlorophenyl)-n-(3-hydroxypropyl)acetamide (CAS 1156897-71-0)
- 2-(4-chlorophenyl)-2-(dimethylamino)propanoic acid (CAS 1157479-33-8)
- Methyl 2-((4-chlorophenyl)amino)-2-methylpropanoate (CAS 1179037-98-9)
- n-(1-(3-Chlorophenyl)ethyl)-2-methoxyacetamide (CAS 1197741-49-3)
- N-(4-chlorophenyl)-2-hydroxy-N-isopropylacetamide (CAS 121431-17-2)
- Methyl 2-(4-chlorophenyl)-2-(ethylamino)acetate (CAS 1218339-60-6)
- 2-[(3-Chlorophenyl)amino]butanohydrazide (CAS 1306738-24-8)
Recommended Standards
- 2-(4-Chlorophenyl)-2-phenylacetonitrile (CAS 4578-80-7)
- 2-Chloro-5-methyl-N-((tetrahydrofuran-2-yl)methyl)pyrimidin-4-amine (CAS 521982-98-9)
- 2-(3-Chlorophenyl)indole, 97% (CAS 23746-77-2)
- 2-Chloro-6-(dimethylamino)-N,N-dimethylisonicotinamide (CAS 2420419-24-3)
- 2,2＇-Azobis(2-Methylpropionamidine) Dihydrochloride (CAS 2997-92-4)
- 4-oxo-3,4-dihydroquinazoline-7-carboxylic acid (CAS 202197-73-7)
- (2-Chloro-4,6-dimethoxypyrimidin-5-yl)boronic acid (CAS 654075-24-8)
- Dimethyl[(3-Bromo-4-methylphenyl)methyl]amine (CAS 1414870-57-7)
- N-(1H-benzo[d]imidazol-2-yl)-2-mercaptoacetamide (CAS 67458-18-8)
- 1,4-Dioxa-9-azadispiro[4.1.4.3]tetradecan-10-one (CAS 1638759-75-7)
- [1,2,4]triazolo[1,5-a]pyrimidin-2-ylmethanamine (CAS 1338670-04-4)
- 7-Bromo-3-iodocinnoline (CAS 1956332-51-6)
- 4-Bromo-2-(difluoromethyl)-5-iodo-3-methoxypyridine (CAS 1806070-25-6)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
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