(S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid CAS 749847-57-2
| CAS No. | 749847-57-2 |
| Molecular Formula | C9H8F3NO2 |
| Molecular Weight | 219.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid.
(S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid (CAS 749847-57-2), molecular formula C9H8F3NO2 and molecular weight 219.16 g/mol, is a CATO reference standard with documented purity and traceability.
(S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid (C9H8F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8F3NO2 |
| Molecular Weight | 219.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- Methyl 2-Amino-5-(trifluoromethyl)benzoate (CAS 117324-58-0)
- Ethyl 2-amino-3,4,5-trifluorobenzoate (CAS 1184500-46-6)
- (R)-4-(1-Amino-2,2,2-trifluoroethyl)benzoic acid (CAS 1212897-03-4)
- (R)-3-(1-Amino-2,2,2-trifluoroethyl)benzoic acid (CAS 1213358-29-2)
- (S)-4-(1-Amino-2,2,2-trifluoroethyl)benzoic acid (CAS 1213548-46-9)
- (S)-3-(1-Amino-2,2,2-trifluoroethyl)benzoic acid (CAS 1213828-28-4)
- 2-Amino-3-(2,3,6-trifluorophenyl)propanoic acid (CAS 1214049-90-7)
- (R)-2-amino-3-(2,4,5-trifluorophenyl)propanoic acid (CAS 1217601-63-2)
Recommended Standards
- (S)-2-amino-3-(2,3,6-trifluorophenyl)propanoic acid (CAS 873429-60-8)
- (S)-2-amino-3-(2,4,6-trifluorophenyl)propanoic acid (CAS 481660-72-4)
- (S)-2-Amino-3-(2,3,5-trifluorophenyl)propanoic acid (CAS 873429-59-5)
- (S)-2-Amino-3-(3,4,5-trifluorophenyl)propanoicacid (CAS 646066-73-1)
- 2-(4-Amino-3-cyano-6-(trifluoromethoxy)pyridin-2-yl)acetic acid (CAS 1804570-65-7)
- Manidipine Hydrochloride Oxidant Body (CAS 104305-93-3)
- Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate (CAS 109882-31-7)
- 2-Bromo-3-chloro-5-fluorobenzaldehyde (CAS 1805210-20-1)
- (4-Bromo-5-chlorofuran-2-yl)(4-methylpiperazin-1-yl)methanone (CAS 1427021-17-7)
- (6-Bromo-2-fluoro-3-methoxyphenyl)(methyl)sulfane (CAS 1822822-76-3)
- 1-tert-Butyl-3-(naphthalen-1-yl)-1H-pyrazolo-[3,4-d]pyrimidin-4-amine hydrochloride (CAS 956025-47-1)
- (E)-N-((1-(2-Phenoxyacetyl)piperidin-4-yl)methyl)-3-(thiophen-2-yl)acrylamide (CAS 1235696-08-8)
- Methyl 3-(methoxymethyl)benzoate (CAS 1515-87-3)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
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