| CAS No. | 749906-88-5 |
| Molecular Formula | C12H7Cl2N3OS |
| Molecular Weight | 312.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
2-Cyano-n-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]acetamide (CAS 749906-88-5), molecular formula C12H7Cl2N3OS and molecular weight 312.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, 2-Cyano-n-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Cyano-n-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C12H7Cl2N3OS |
| Molecular Weight | 312.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |