3-Amino-5-(4-chlorophenyl)thiophene-2-carbohydrazide CAS 749920-74-9
| CAS No. | 749920-74-9 |
| Molecular Formula | C11H10ClN3OS |
| Molecular Weight | 267.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Amino-5-(4-chlorophenyl)thiophene-2-carbohydrazide (CAS 749920-74-9), molecular formula C11H10ClN3OS and molecular weight 267.73 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-5-(4-chlorophenyl)thiophene-2-carbohydrazide (C11H10ClN3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10ClN3OS |
| Molecular Weight | 267.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- Methyl 3-amino-5-(2-chlorophenyl)thiophene-2-carboxylate (CAS 107818-29-1)
- 1114597-04-4 2-Amino-6-{[(4-chlorophenyl)thio]methyl}-pyrimidin-4-ol 8794AC C11H10ClN3OS (CAS 1114597-04-4)
- Methyl 3-amino-4-(3-chlorophenyl)thiophene-2-carboxylate (CAS 1325306-18-0)
- Methyl 3-amino-4-(4-chlorophenyl)thiophene-2-carboxylate (CAS 156274-30-5)
- 6-Amino-2-((3-chlorobenzyl)thio)pyrimidin-4(3H)-one (CAS 166751-40-2)
- Methyl 2-amino-4-(2-chlorophenyl)thiophene-3-carboxylate (CAS 350997-11-4)
- Methyl 2-amino-4-(4-chlorophenyl)thiophene-3-carboxylate (CAS 350997-10-3)
- Methyl 3-amino-4-(2-chlorophenyl)thiophene-2-carboxylate (CAS 925005-57-8)
Recommended Standards
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- 4-{[6-chloro-2-(methylsulfanyl)pyrimidin-4-yl]amino}phenol (CAS 478258-36-5)
- 7-Nitro-9H-benzo[e][1,2,4]triazolo[5,1-b][1,3]thiazin-9-ol (CAS 663206-21-1)
- methyl 5-(4-chlorophenyl)-1-methyl-1H-pyrazole-3-carboxylate (CAS 1275687-89-2)
- 5-(tert-butylamino)-N’-hydroxypyridine-2-carboximidamide (CAS 1443987-56-1)
- Copper(II) terephthalate trihydrate (CAS 28758-10-3)
- Dichloromethylsilane (CAS 75-54-7)
- (2R,3S,5R)-5-(4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 187479-00-1)
- (3-Methyl-thiophen-2-ylmethyl)-(3-morpholin-4-yl-propyl)-amine hydrochloride 0221AD 1185294-58-9 C13H23ClN2OS (CAS 1185294-58-9)
- 5-(2-Bromophenyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol (CAS 917747-80-9)
- 1,3-Isobenzofurandione, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (CAS 30525-36-1)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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