2-(4-Bromophenyl)-4-chloro-3H-imidazo[4,5-c]pyridine CAS 75008-00-3

Description

The occurrence of 2-(4-Bromophenyl)-4-chloro-3H-imidazo[4,5-c]pyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(4-Bromophenyl)-4-chloro-3H-imidazo[4,5-c]pyridine (CAS 75008-00-3), molecular formula C12H7BrClN3 and molecular weight 308.56 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(4-Bromophenyl)-4-chloro-3H-imidazo[4,5-c]pyridine (C12H7BrClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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