4-[(5-bromopyridin-2-yl)oxy]phenol CAS 75053-81-5
| CAS No. | 75053-81-5 |
| Molecular Formula | C11H8BrNO2 |
| Molecular Weight | 266.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(5-bromopyridin-2-yl)oxy]phenol.
CATO supplies 4-[(5-bromopyridin-2-yl)oxy]phenol (CAS 75053-81-5), a certified reference material (molecular formula C11H8BrNO2, MW 266.09 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 4-[(5-bromopyridin-2-yl)oxy]phenol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 266.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(5-bromopyridin-2-yl)oxy]phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8BrNO2 |
| Molecular Weight | 266.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related bromopyridin Standards
- 1216804-34-0 6-[(5-Bromopyridin-3-yl)oxy]pyridin-3-amine KS-00003TRB (CAS 1216804-34-0)
- (5-Bromopyridin-3-yl)(1-methyl-1H-imidazol-2-yl)methanone (CAS 889944-40-5)
- 3-(5-Bromopyridin-3-yl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603067-87-4)
- (5-Bromopyridin-3-yl)methyl methanesulfonate (CAS 145743-86-8)
- (6-Bromopyridin-2-yl)methyl methanesulfonate (CAS 557789-12-5)
- 1-(5-Bromopyridin-3-yl)piperidine-4-carbonitrile (CAS 1289110-84-4)
- N-(5-Bromopyridin-3-yl)ethanesulfonamide (CAS 1086065-44-2)
- N-(5-bromopyridin-3-yl)-N-methylmethanesulfonamide (CAS 1240287-01-7)
Recommended Standards
- 4,6-Dichloro-1-(pyridin-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 2060595-41-5)
- 4-Amino-5-bromo-2-phenylpyridazin-3(2H)-one (CAS 37626-96-3)
- 3-Bromo-1-methyl-5-(pyrimidin-4-yl)pyridin-2(1H)-one (CAS 89996-20-3)
- 4-Amino-5-bromo-6-phenylpyridazin-3(2H)-one (CAS 350578-55-1)
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