2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethanamine CAS 751476-91-2
| CAS No. | 751476-91-2 |
| Molecular Formula | C10H12F3NO2 |
| Molecular Weight | 235.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethanamine.
2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethanamine (CAS 751476-91-2), molecular formula C10H12F3NO2 and molecular weight 235.20 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethanamine (C10H12F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 235.20 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12F3NO2 |
| Molecular Weight | 235.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoroethoxy Standards
- 2-[4-(2,2,2-Trifluoroethoxy)phenoxy]ethan-1-amine (CAS 189876-49-1)
- 6-((2,2,2-Trifluoroethoxy)methyl)nicotinic acid (CAS 1072855-75-4)
- 1-(Trifluoroethoxy)-2-methyl-4-nitrobenzene (CAS 96308-26-8)
- 3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinecarboxylic Acid (CAS 463299-54-9)
- Methyl 6-(2,2,2-trifluoroethoxy)nicotinate (CAS 287979-27-5)
- 2-Methyl-6-(2,2,2-trifluoroethoxy)pyrimidine-4-carboxylic acid (CAS 1710695-95-6)
- 4-Methyl-2-(2,2,2-trifluoroethoxy)pyrimidine-5-carboxylic acid (CAS 914201-23-3)
- 6-(2,2,2-Trifluoroethoxy)pyridine-3-carbothioamide (CAS 175277-59-5)
Recommended Standards
- 2-[[2-Fluoro-5-(trifluoromethyl)phenyl]thio]acetonitrile (CAS 304901-46-0)
- 2-Amino-6-(2-oxopropyl)pteridine-4,7(1H,8H)-dione (CAS 784-76-9)
- 2,3-Dimethyl-5-nitro-2,3-dihydrophthalazine-1,4-dione (CAS 858243-19-3)
- 2-Carbamoyl-7-methoxypyrazolo[1,5-a]pyridine-5-carboxylic acid (CAS 2721374-91-8)
- Methyl 8-isopropyl-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 187454-83-7)
- 2-chloro-N-(1-acetylpiperidin-4-yl)acetamide (CAS 1152621-92-5)
- Methyl 1-oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylate (CAS 80314-96-1)
- 2-(5-(((5-(2-Nitrophenyl)-1,3,4-oxadiazol-2-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)phenol (CAS 332883-11-1)
- N-(3-(Trifluoromethoxy)benzyl)-[3,4'-bipyridin]-5-amine (CAS 821784-76-3)
- 8-Methyl-[1,2,4]triazolo[4,3-a]pyridin-3-amine (CAS 4926-25-4)
- 4-(2,4-Difluoro-phenyl)-piperidine hydrochloride (CAS 941711-38-2)
- (R)-5-bromo-6-chloro-2,3-dihydro-1H-inden-1-amine (CAS 1259666-89-1)
- AI-3 (CAS 882288-28-0)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
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