5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol CAS 75175-84-7
| CAS No. | 75175-84-7 |
| Molecular Formula | C12H7F3N4O |
| Molecular Weight | 280.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (C12H7F3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (CAS 75175-84-7) is a high-purity analytical reference standard with the molecular formula C12H7F3N4O and a molecular weight of 280.21 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7F3N4O |
| Molecular Weight | 280.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Trifluoromethyl Standards
- 3-Phenyl-7-(trifluoromethyl)-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-amine (CAS 1338218-84-0)
- 1-[3-(trifluoromethyl)phenyl]-1h,4h,5h-pyrazolo[3,4-d]pyrimidin-4-one (CAS 949654-67-5)
- 3-phenyl-4-(trifluoromethyl)isoxaZolo[5,4-b]pyridin-6(7h)-one (CAS 1018047-90-9)
- 3-(Trifluoromethyl)-1H-benzo[g]indazole-5-carboxylic acid (CAS 1065076-42-7)
- 2-Methyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1008773-97-4)
- Methyl 5-(trifluoromethyl)-[1,1'-biphenyl]-3-carboxylate (CAS 101640-74-8)
- 2-Methyl-2-(trifluoromethyl)-[1,1-biphenyl]-4-carboxylic acid (CAS 1140462-04-9)
- 2-(5-(trifluoromethyl)biphenyl-2-yl)acetic acid (CAS 1214346-33-4)
Recommended Standards
- 4,4,5,5-Tetramethyl-2-(6-neopentyl-3,6-dihydro-2H-pyran-4-yl)-1,3,2-dioxaborolane (CAS 2643317-87-5)
- 2-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1196131-36-8)
- 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2043962-01-0)
- 2-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1420885-96-6)
- 2-(2-Chloro-4-(difluoromethyl)-6-fluoropyridin-3-yl)acetonitrile (CAS 1805383-81-6)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic acid (CAS 2044702-38-5)
- 6-Bromo-4-chloro-2-(methylsulfanyl)quinazoline (CAS 1003043-76-2)
- 3-Iodoimidazo[1,2-b]pyridazin-6(5H)-one (CAS 1202493-40-0)
- Dydrogesterone-d6 (CAS CATO-C4X-21833)
- (S)-2-(3-Bromophenyl)piperidine (CAS 1228557-44-5)
- Quinazoline-2,4-dithiol (CAS 5993-69-1)
- 4-(2-(2-(Naphthalen-2-yloxy)acetyl)hydrazinyl)-4-oxobutanoic acid (CAS 161954-97-8)
- 3-(4-Iodophenyl)-4-methyl-1h-pyrazol-5-amine (CAS 1187027-02-6)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com