5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine CAS 75175-86-9

Purity 97%+In StockPharmaceutical Standards
CAS No.75175-86-9
Molecular FormulaC12H7F3N4
Molecular Weight264.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine CAS 75175-86-9 chemical structure

Description

The occurrence of 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 75175-86-9) is a high-purity analytical reference standard with the molecular formula C12H7F3N4 and a molecular weight of 264.21 g/mol.

The molecular framework of 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (C12H7F3N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H7F3N4
Molecular Weight264.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1978
Halogen ContentF-containing
Nitrogen Atoms4

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