| CAS No. | 75175-86-9 |
| Molecular Formula | C12H7F3N4 |
| Molecular Weight | 264.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 75175-86-9) is a high-purity analytical reference standard with the molecular formula C12H7F3N4 and a molecular weight of 264.21 g/mol.
The molecular framework of 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (C12H7F3N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C12H7F3N4 |
| Molecular Weight | 264.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |