1-(4-Fluorophenyl)cyclopropanemethanamine CAS 75180-46-0
| CAS No. | 75180-46-0 |
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 165.21 g/mol gives 1-(4-Fluorophenyl)cyclopropanemethanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-Fluorophenyl)cyclopropanemethanamine (CAS 75180-46-0), molecular formula C10H12FN and molecular weight 165.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 1-(4-Fluorophenyl)cyclopropanemethanamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 1-(2-Fluorophenyl)cyclobutanamine (CAS 1017391-62-6)
- (R)-3-(4-fluorophenyl)pyrrolidine (CAS 1048703-18-9)
- 3-(4-Fluorophenyl)cyclobutan-1-amine (CAS 1156295-31-6)
- 3-(3-Fluorophenyl)cyclobutan-1-amine (CAS 1156296-01-3)
- 1-(4-Fluorophenyl)but-3-en-1-amine (CAS 1159883-05-2)
- (S)-1-(2-fluorophenyl)but-3-en-1-amine (CAS 1181817-72-0)
- (S)-2-(2-fluorophenyl)pyrrolidine (CAS 1211109-18-0)
- (2-(4-Fluorophenyl)cyclopropyl)methanamine (CAS 1226363-19-4)
Recommended Standards
- 1-(4-Fluorophenyl)cyclobutanamine (CAS 920501-69-5)
- 1-(4H-Thieno[3,2-b]pyrrol-5-yl)ethan-1-one (CAS 60664-20-2)
- 1-(4-Fluorobenzyl)cyclopropan-1-amine (CAS 864961-01-3)
- 1-(Methoxymethyl)cyclopropane-1-sulfonamide (CAS 681808-28-6)
- N-{4-[5-(Chloromethyl)-1,3-oxazolidin-2-yl]-phenyl}-N,N-dimethylamine (CAS 17996-49-5)
- 4,4'-Bi-4H-1,2,4-triazole (CAS 16227-15-9)
- (S)-2-amino-5-((S)-2,4-diaminobutanamido)pentanoic acid (CAS CATO-C3D-2272)
- (1,2-Dimethylhexahydropyridazin-3-yl)methanol (CAS 126936-88-7)
- 3-((2-Nitro-5-(pyrrolidin-1-yl)phenyl)amino)propyl acetate (CAS 332390-80-4)
- 2-(Dimethylamino)ethyl 3-amino-4-chlorobenzoate (CAS 13930-34-2)
- 1-Hexyl-1-methylpyrrolidin-1-ium Bis((trifluoromethyl)sulfonyl)amide (CAS 380497-19-8)
- Paclitaxel Impurity 36 (CAS 153415-46-4)
- 2-Amino-6-(dimethylamino)nicotinaldehyde (CAS 1289035-29-5)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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