N-(4-Chlorophenyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-amine CAS 75220-48-3
| CAS No. | 75220-48-3 |
| Molecular Formula | C10H11ClN2S |
| Molecular Weight | 226.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures N-(4-Chlorophenyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
N-(4-Chlorophenyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-amine (CAS 75220-48-3) is a high-purity analytical reference standard with the molecular formula C10H11ClN2S and a molecular weight of 226.73 g/mol.
The molecular framework of N-(4-Chlorophenyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-amine (C10H11ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H11ClN2S |
| Molecular Weight | 226.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-Chlorophenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine (CAS 103039-04-9)
- N-(2-Chlorophenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine (CAS 27779-16-4)
- n-(4-Chlorophenyl)-4-methyl-4,5-dihydro-1,3-thiazol-2-amine (CAS 379728-04-8)
- n-[(4-chlorophenyl)methyl]-4,5-dihydro-1,3-thiazol-2-amine (CAS 72239-29-3)
- 2-((4-Chlorophenyl)thio)-1-cyclopropylethan-1-one (CAS 1344305-58-3)
- 2-((3-Chlorophenyl)thio)-1-cyclopropylethan-1-one (CAS 1344328-45-5)
- [4-(4-chlorophenyl)morpholin-2-yl]methanamine (CAS 1017166-10-7)
- n-(4-Chlorophenyl)-2-(propylamino)acetamide (CAS 1021230-54-5)
Recommended Standards
- N-(3-Chloro-2-methylphenyl)-4,5-dihydro-1,3-thiazol-2-amine (CAS 36318-59-9)
- 2-(4-Chloro-3,5-dimethylphenyl)pentan-2-ol (CAS 1443302-82-6)
- 2-(4-Chloro-3,5-dimethylphenyl)-3-methylbutan-2-ol (CAS 1443306-77-1)
- 5-Chloro-1-propyl-1h-1,3-benzodiazole-2-thiol (CAS 790271-30-6)
- (S)-3-(3-Methoxyphenyl)-2-oxooxazolidine-5-carboxylic acid (CAS 918543-56-3)
- 2-Chloro-4-methyl-6-(1H-pyrazol-1-yl)pyrimidine (CAS 1248241-65-7)
- tert-Butyl 3-cyano-3-fluoropyrrolidine-1-carboxylate (CAS 1334675-01-2)
- 3,6-Dibromo-2-(bromomethyl)pyridine (CAS 1227563-56-5)
- Diphenyl-pyrrolidin-3-yl-methanol (CAS 5731-19-1)
- 3,3,3-Trifluoropropanenitrile (CAS 20530-38-5)
- (5-Cyclopropylthiophen-2-yl)boronic acid (CAS 1913240-52-4)
- 1-Bromo-5-(bromomethyl)-2,3-difluorobenzene (CAS 1807172-44-6)
- 6-Fluoro-1,2,3,4-tetrahydroquinolin-8-amine (CAS 210751-53-4)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com