Methyl (2S,4S)-4-(4-fluorophenoxy)pyrrolidine-2-carboxylate hydrochloride CAS 753403-75-7
| CAS No. | 753403-75-7 |
| Molecular Formula | C12H14FNO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl (2S,4S)-4-(4-fluorophenoxy)pyrrolidine-2-carboxylate hydrochloride.
Methyl (2S,4S)-4-(4-fluorophenoxy)pyrrolidine-2-carboxylate hydrochloride (CAS 753403-75-7), molecular formula C12H14FNO3HCl and molecular weight 275.70 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Methyl (2S,4S)-4-(4-fluorophenoxy)pyrrolidine-2-carboxylate hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 275.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14FNO3 HCl |
| Molecular Weight | 275.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-(1-Isopropoxyethyl)naphthalen-1-amine (CAS 1394023-18-7)
- 1-(Isopropoxymethyl)cyclopropane-1-carboxylic acid (CAS 1387563-33-8)
- 6-Fluoro-2-(methylthio)-5-(trifluoromethyl)pyrimidin-4(1H)-one (CAS 100499-06-7)
- 7-Fluoro-2,3-dimethylquinoxaline-5-carboxylic acid (CAS 1193388-35-0)
- 2-(2-(2,4-Dichlorophenoxy)propanoyl)-N-(4-methoxyphenyl)hydrazine-1-carbothioamide (CAS 903815-50-9)
- 5-(Piperidin-1-ylsulfonyl)-1-(4-vinylbenzyl)pyridin-2(1H)-one (CAS 1251552-58-5)
- 2-Formylphenyl trifluoromethyl sulphide 2-[(Trifluoromethyl)sulphanyl]benzaldehyde 2-[(trifluoromethyl)sulfanyl]benzaldehyde 57830-48-5 (CAS 57830-48-5)
- Iodoantipyrine (CAS 129-81-7)
- (2e)-3-(1h-Pyrrol-2-yl)prop-2-enoic acid (CAS 49653-15-8)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com