2-(dichloromethyl)-5-methyl-1,3,4-thiadiazole CAS 75341-27-4
| CAS No. | 75341-27-4 |
| Molecular Formula | C4H4Cl2N2S |
| Molecular Weight | 183.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(dichloromethyl)-5-methyl-1,3,4-thiadiazole (C4H4Cl2N2S) contains a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 2-(dichloromethyl)-5-methyl-1,3,4-thiadiazole (CAS 75341-27-4), a certified reference material (molecular formula C4H4Cl2N2S, MW 183.06 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H4Cl2N2S |
| Molecular Weight | 183.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related dichloromethyl Standards
- 1,1-Dichloromethyl Ether (CAS 20524-86-1)
- 5-Dichloromethyl-[1,3,4]thiadiazol-2-ylamine (CAS 32546-30-8)
- 3-(Dichloromethyl)benzonitrile (CAS 93632-91-8)
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- 1-(Dichloromethyl)-4-fluorobenzene (CAS 456-19-9)
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Recommended Standards
- 1-Bromo-6-fluorohexane (CAS 373-28-4)
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- (4,5-Dichlorothiophen-2-yl)methanol (CAS 89284-46-8)
- 2,1,3-Benzoselenadiazole (CAS 273-15-4)
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- 2-Hydroxy-1-methyl-6-phenylimidazo(4,5-b)pyridine D3 (CAS 1020719-48-5)
- 6-Isopropylpyridine-3-carbothioamide (CAS 1256812-37-9)
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- Dehydrotomatine (CAS 157604-98-3)
- (((16,16,17,17,18,18,18-Heptafluorooctadecyl)oxy)methyl)benzene (CAS 102197-77-3)
- Peptide 441 (CAS CATO-CPTD788441)
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