2-Amino-6-(4-chlorophenyl)-4-phenylnicotinonitrile CAS 75356-07-9
| CAS No. | 75356-07-9 |
| Molecular Formula | C18H12ClN3 |
| Molecular Weight | 305.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-6-(4-chlorophenyl)-4-phenylnicotinonitrile.
2-Amino-6-(4-chlorophenyl)-4-phenylnicotinonitrile (CAS 75356-07-9), molecular formula C18H12ClN3 and molecular weight 305.76 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-6-(4-chlorophenyl)-4-phenylnicotinonitrile (C18H12ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12ClN3 |
| Molecular Weight | 305.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
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- 3-Amino-1-(4-chlorophenyl)-6-(dimethylamino)-1H,4H-pyrazolo[3,4-d][1,3]oxazin-4-one (CAS 250713-83-8)
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Recommended Standards
- 2-((4-Chlorobenzylidene)amino)-4-phenyl-1H-pyrrole-3-carbonitrile (CAS 303149-96-4)
- 2-Chloro-1-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-1H-pyrrol-3-yl]ethanone (CAS 731003-81-9)
- 1-[1-(1,3-Benzodioxol-5-ylmethyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-chloroethanone (CAS 731826-79-2)
- 2-Chloro-9-phenoxyacridine (CAS 61981-62-2)
- 2,2,4,4-Tetramethyl-3,8,11,14,17-pentaoxa-2,4-disilaoctadecane (CAS 855996-83-7)
- 6-(Allyloxy)-2,3-dichlorobenzyl Alcohol (CAS 1823900-94-2)
- (1S,3S)-3-((tert-Butoxycarbonyl)amino)cyclopentanecarboxylic acid (CAS 161601-29-2)
- 5-Chloro-2-(pentyloxy)benzaldehyde (CAS 81995-30-4)
- 6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6-azaspiro[3.4]octane-8-carboxylic acid (CAS 2127012-32-0)
- 3-Methyl-6-(trimethylsilyl)-3H-imidazo[4,5-b]pyridine (CAS 1171920-66-3)
- 2,7-Difluoronaphthalen-1-ol (CAS 2852767-36-1)
- 2-(4-Methoxyphenyl)-2-oxoethyl 2-(methylthio)nicotinate (CAS 485351-18-6)
- 2-(1-methyl-4-piperidyl)acetonitrile (CAS 164926-88-9)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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