(3-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine CAS 754173-67-6
| CAS No. | 754173-67-6 |
| Molecular Formula | C8H8ClN3 |
| Molecular Weight | 181.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 181.62 g/mol gives (3-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(3-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine (CAS 754173-67-6), molecular formula C8H8ClN3 and molecular weight 181.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, (3-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClN3 |
| Molecular Weight | 181.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1000340-14-6)
- 4-Chloro-7-methoxy-1H-indole (CAS 1000341-80-9)
- 4-Chloro-5-ethyl-7h-pyrrolo[2,3-d]pyrimidine (CAS 1004992-44-2)
- 4-Chloro-1-ethyl-1H-imidazo[4,5-c]pyridine (CAS 1025509-11-8)
- 6-Chloro-2-ethylbenzoxazole (CAS 1027019-12-0)
- 6-Chloro-1-methyl-1H-indazol-3-amine (CAS 1031927-22-6)
- 4-chloro-1-methyl-1H-1,3-benzodiazol-2-amine (CAS 1037670-19-1)
- 5-Chloro-2,3-dimethylimidazo[4,5-b]pyridine (CAS 1044770-63-9)
Recommended Standards
- (2-Chloropyridin-4-yl)(cyclopropyl)methanone (CAS 898785-12-1)
- (3-Chloro-1H-pyrrolo[2,3-c]pyridin-5-yl)methanamine (CAS 267876-27-7)
- (1E,2Z)-3-chloro-3-phenylacrylaldehyde oxime (CAS 72806-43-0)
- (4-Chloro-1h-indol-2-yl)methanol (CAS 53590-41-3)
- 4-Butoxy-N-(2-hydroxy-3-methoxy-2-methylpropyl)benzamide (CAS 1334370-84-1)
- 2-Phenyl-3-(m-tolyl)pyrimidin-4(3H)-one (CAS 89069-67-0)
- (7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)methanol (CAS 2387595-33-5)
- (4-Chloro-3-fluorophenyl)(2,4-difluorobenzyl)sulfane (CAS 1443352-93-9)
- 4-(Difluoromethoxy)-1-fluoro-2-(trifluoromethyl)benzene (CAS 1417566-45-0)
- 5-(4-(Trifluoromethyl)phenyl)-1,3,4-oxadiazole-2-carbaldehyde (CAS 944897-90-9)
- 3-((4-Ethoxyphenyl)amino)-1-(4-methoxyphenyl)propan-1-one (CAS 477319-99-6)
- 1-[3-(phenoxymethyl)-1,2,4-oxadiazol-5-yl]ethan-1-amine (CAS 1082925-46-9)
- Ethyl 1-benzyl-5-methyl-1H-1,2,3-triazole-4-carboxylate (CAS 133992-58-2)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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