Ethyl (5-bromo-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetate CAS 754235-62-6
| CAS No. | 754235-62-6 |
| Molecular Formula | C12H10BrNO4 |
| Molecular Weight | 312.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl (5-bromo-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetate.
Ethyl (5-bromo-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetate (CAS 754235-62-6) is a high-purity analytical reference standard with the molecular formula C12H10BrNO4 and a molecular weight of 312.12 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Ethyl (5-bromo-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10BrNO4 |
| Molecular Weight | 312.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-Cyclopropyl-6-(difluoromethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 2446483-77-6)
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- 4-(5-Bromo-2,3-dioxoindolin-1-yl)butanoic acid (CAS 928712-48-5)
- Methyl 2-(2,5-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate (CAS 2505462-09-7)
- Trityl 2,2,2-trifluoroacetate (CAS CATO-C3D-4695)
- 4-Fluoro-3-(tetrahydro-2h-pyran-4-yl)-1h-indole (CAS 1707358-78-8)
- N-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyrimidinamine (CAS 1218791-48-0)
- n-(2-Methoxybenzyl)pentan-3-amine (CAS 355382-11-5)
- 3-Diethylamino Acetaminophen-d10 (CAS 1794789-22-2)
- Cbz-b-Ala-b-Ala (CAS 69281-02-3)
- 2-(4-Chlorophenyl)-3-methoxypent-2-enenitrile (CAS 100121-94-6)
- (1-Isopropyl-1H-pyrazol-5-yl)boronic acid (CAS 839714-33-9)
- 2-(2-(5-Chlorothiophen-2-yl)acetamido)thiophene-3-carboxamide (CAS 921546-68-1)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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