1-(Naphthalen-1-ylmethyl)-1h-pyrazol-5-amine CAS 75427-10-0
| CAS No. | 75427-10-0 |
| Molecular Formula | C14H13N3 |
| Molecular Weight | 223.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Naphthalen-1-ylmethyl)-1h-pyrazol-5-amine.
1-(Naphthalen-1-ylmethyl)-1h-pyrazol-5-amine (CAS 75427-10-0), molecular formula C14H13N3 and molecular weight 223.27 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C14H13N3, 1-(Naphthalen-1-ylmethyl)-1h-pyrazol-5-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H13N3 |
| Molecular Weight | 223.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 3 |
Related Naphthalen Standards
- 1-Methyl-3-(naphthalen-2-yl)-1h-pyrazol-5-amine (CAS 1152648-32-2)
- 1-(Naphthalen-2-ylmethyl)-1H-pyrazol-4-amine (CAS 1240567-95-6)
- 1-(Naphthalen-1-ylmethyl)-1h-pyrazol-4-amine (CAS 512810-08-1)
- 1-(naphthalen-1-yl)-1H-pyrrole-2,5-dione 1-Naphthalen-1-yl-pyrrole-2,5-dione 3369-39-9 (CAS 3369-39-9)
- Naphthalen-2-yl dihydrogen phosphate (CAS 13095-41-5)
- 1-Ethyl-4-(naphthalen-1-yl)-1H-pyrazole (CAS 1394021-08-9)
- 5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3(2H)-one (CAS 1192140-15-0)
- 5-(naphthalen-2-yl)-1,2,4-triazin-3-amine (CAS 1152506-17-6)
Recommended Standards
- 1-(p-Tolyl)-1H-benzo[d]imidazol-5-amine (CAS 53897-96-4)
- 1-(Furan-2-ylmethyl)piperidine-3-carbohydrazide (CAS 415937-00-7)
- 1,1-Diethyl-3-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)guanidine (CAS 819804-17-6)
- 1-(Dimethylamino)-9H-fluoren-9-one (CAS 205526-41-6)
- N-((5-Cyclopropyl-1-methyl-1H-pyrazol-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide (CAS 1448060-43-2)
- 6-(N-Methyl-3,4-xylidino)uracil (CAS 36995-89-8)
- (E)-Methyl 4-aminobut-2-enoate hydrochloride (CAS 213125-87-2)
- 2-Chloro-3,6-dimethylpyridine (CAS 72093-14-2)
- N,N'-(9,10-dioxo-9,10-dihydroanthracene-1,4-diyl)bis(2,2,2-trifluoroacetamide) (CAS 341966-12-9)
- 5-[4-(1H-Pyrazol-1-yl)phenyl]-1,3-oxazole (CAS 955976-36-0)
- Ethyl 2-((thiophen-2-ylmethyl)amino)acetate (CAS 79714-08-2)
- Potassium (2-cyanophenyl)trifluoroborate (CAS 929038-12-0)
- 3-Bromo-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one (CAS 2059940-72-4)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
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