Methyl 6-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylate CAS 7545-52-0
| CAS No. | 7545-52-0 |
| Molecular Formula | C11H8ClNO3 |
| Molecular Weight | 237.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 6-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 6-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 7545-52-0), molecular formula C11H8ClNO3 and molecular weight 237.64 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H8ClNO3, Methyl 6-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 237.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 6-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO3 |
| Molecular Weight | 237.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 3-Chloro-5-cyclopropylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1011354-08-7)
- 2-Chloro-8-methoxyquinoline-3-carboxylic acid (CAS 1017157-83-3)
- 6-Chloro-4-hydroxy-2-methylquinoline-3-carboxylic acid (CAS 103566-34-3)
- 1-(3-Chloro-2-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042534-76-8)
- 1-(3-Chloro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042604-53-4)
- 2-Chloro-6-hydroxy-7-methoxyquinoline-3-carbaldehyde (CAS 1046138-52-6)
- Methyl 8-chloro-4-hydroxyquinoline-2-carboxylate (CAS 1065074-57-8)
- 2-(8-Chloro-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1092288-62-4)
Recommended Standards
- Methyl 6-chloro-3-formyl-1H-indole-2-carboxylate (CAS 893730-96-6)
- Methyl 7-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 5347-19-3)
- Methyl 5-chloro-3-formyl-1H-indole-2-carboxylate (CAS 843619-25-0)
- Methyl 8-chloro-4-hydroxyquinoline-3-carboxylate (CAS 942227-33-0)
- N-(5-Amino-2-methoxy-phenyl)-3,4-dichloro-benzenesulfonamide (CAS 522624-60-8)
- 6-Aminoquinoxaline-5-carbonitrile (CAS 130278-26-1)
- Methyl 5-(pyrrolidin-1-ylmethyl)furan-2-carboxylate (CAS 26095-06-7)
- 4-Chlorophenyl Phenyl-d5 Ether (CAS 93951-85-0)
- Ethyl 2-amino-6-(1-ethoxy-2-methyl-1-oxopropan-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 914202-76-9)
- 1-(3-(Aminomethyl)morpholino)ethanone (CAS 1595795-40-6)
- Ethyl 11-fluoroundecanoate (CAS 332-98-9)
- Ethyl N'-(3-nitroquinolin-4-yl)acetohydrazonate (CAS 51093-97-1)
- Tert-butyl 2-(prop-1-en-2-yl)pyrrolidine-1-carboxylate (CAS 1334492-15-7)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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