6-Fluorochroman-2-one CAS 75487-95-5
| CAS No. | 75487-95-5 |
| Molecular Formula | C9H7FO2 |
| Molecular Weight | 166.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Fluorochroman-2-one (CAS 75487-95-5), molecular formula C9H7FO2 and molecular weight 166.15 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Fluorochroman-2-one (C9H7FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 166.15 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Fluorochroman-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7FO2 |
| Molecular Weight | 166.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
Related Fluorochroman Standards
- 7-Fluorochroman-4-one (CAS 113209-68-0)
- 6-Fluorochroman-3-one (CAS 944904-05-6)
- 6-Fluorochroman-4-one (CAS 66892-34-0)
- 7-Fluorochroman-3-one (CAS 944904-13-6)
- (S)-8-Fluorochroman-4-amine (CAS 1003887-62-4)
- 5-Fluorochroman-4-amine (CAS 1018978-82-9)
- (S)-5-Fluorochroman-4-amine (CAS 1018978-84-1)
- (S)-6-Fluorochroman-4-amine (CAS 1018978-85-2)
Recommended Standards
- 6-Fluorobenzoxazole-2-methanamine (CAS 944907-47-5)
- 6-Fluoro-4-methoxy-1H-indazole (CAS 885522-57-6)
- 6-Fluoro-3-methyl-1,2-benzoxazol-5-amine (CAS 221559-22-4)
- 7-Amino-5-fluoroindolin-2-one (CAS 945381-62-4)
- n-Ethyl-n-(2-hydroxyethyl)-2,5-dimethylthiophene-3-sulfonamide (CAS 1183989-38-9)
- 2-(Propylthio)pyrimidine-4-carbaldehyde (CAS 219729-65-4)
- Pre-Vitamin D3 Decanoate (CAS 927822-18-2)
- (S)-6-(5-((1-Methylpyrrolidin-2-yl)methoxy)pyridin-3-yl)hexan-1-ol (CAS 820231-76-3)
- 3-Fluorophenethyl acetate (CAS 59163-71-2)
- 2,2-Difluoropropyl Chloride (CAS 420-99-5)
- Olmesartan Impurity 85 (CAS CATO-C4X-109785)
- (2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-(3-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol (CAS 52571-71-8)
- 4-Bromo-3-fluoropicolinic acid (CAS 1807209-95-5)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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