8-Nitroquinazoline CAS 7557-05-3
| CAS No. | 7557-05-3 |
| Molecular Formula | C8H5N3O2 |
| Molecular Weight | 175.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-Nitroquinazoline (CAS 7557-05-3) is a high-purity analytical reference standard with the molecular formula C8H5N3O2 and a molecular weight of 175.14 g/mol.
The molecular framework of 8-Nitroquinazoline (C8H5N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 8-Nitroquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5N3O2 |
| Molecular Weight | 175.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 3 |
Related Nitroquinazoline Standards
- 6-Nitroquinazoline (CAS 7556-95-8)
- 7-Nitroquinazoline (CAS 7557-00-8)
- 2-Methyl-6-nitroquinazoline (CAS 515832-80-1)
- 2-Methyl-7-nitroquinazoline (CAS 455279-78-4)
- 6-Nitroquinazoline-2,4-diamine (CAS 7154-34-9)
- 8-Nitroquinazoline-2,4-diol (CAS 174565-61-8)
- 6-Nitroquinazoline-4(1H)-thione (CAS 13116-83-1)
- 7-Nitroquinazoline-2,4(1H,3H)-dione (CAS 174565-63-0)
Recommended Standards
- 8-Nitrocinnoline (CAS 2942-37-2)
- Dimethyloxaloylglycine (CAS 89464-63-1)
- Ethyl 2-nitro-3-oxobutanoate (CAS 51026-98-3)
- 7-Nitrocinnoline (CAS 817209-45-3)
- 1-Acetyl-5-bromo-6-chloro-1H-indol-3-yl acetate (CAS 108847-96-7)
- Benzyl 4-((2-hydroxyethyl)thio)piperidine-1-carboxylate (CAS 1353955-67-5)
- Bis-PEG1-acid (CAS 5961-83-1)
- 3-Ethynyl-5-(trifluoromethyl)phenol (CAS 1863968-18-6)
- 1-(4-(Trifluoromethyl)phenyl)cyclopentan-1-amine hydrochloride (CAS 1222098-17-0)
- (5S)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]Heptane-2-carboxylic acid (CAS 1232134-74-5)
- (R)-Atenolol (CAS 56715-13-0)
- Tert-butyl (4aS,6R,7aR)-6-aminooctahydro-2H-cyclopenta[c]pyridine-2-carboxylate (CAS 1932206-00-2)
- 4-Chloro-3,5-difluoroaniline (CAS 2613-33-4)
- Cycloaspeptide A (CAS 109171-13-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com