N-(7-Chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-2-yl)-N-methyl- acetamide CAS 7563-73-7
| CAS No. | 7563-73-7 |
| Molecular Formula | C18H16ClN3O2 |
| Molecular Weight | 341.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(7-Chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-2-yl)-N-methyl- acetamide (C18H16ClN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies N-(7-Chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-2-yl)-N-methyl- acetamide (CAS 7563-73-7), a certified reference material (molecular formula C18H16ClN3O2, MW 341.79 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(7-Chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-2-yl)-N-methyl- acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O2 |
| Molecular Weight | 341.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- N-(6-Chlorobenzo[d]thiazol-2-yl)-2-(2,4-dioxothiazolidin-5-yl)acetamide (CAS 880301-25-7)
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- N-(2-((4-chlorophenyl)sulfonyl)ethyl)-4-fluorobenzamide (CAS 338423-94-2)
- 869937-73-5 tert-Butyl 4-(5-chloro-2-nitrophenyl)tetrahydro-1(2H)-pyrazinecarboxylate MFCD11553047 (CAS 869937-73-5)
- 5-Ethynylquinoxaline (CAS 1146124-07-3)
- 4-Cyclohexyl-benzaldehyde (CAS 27634-89-5)
- (S)-2-Aminopropan-1-ol hydrochloride (CAS 17016-91-0)
- (11bS)-N-allyl-N-benzhydryl-2,6-diphenyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 2375836-78-3)
- Oleuroside (CAS 116383-31-4)
- 4-methoxy-5,8,8-trimethylbicyclo[3.2.1]oct-3-en-2-one (CAS 91881-13-9)
- 5-Amino-3-methyl-1-p-tolylpyrazole (CAS 62535-60-8)
- 2-Fluoro-N-(6-((2-((furan-2-ylmethyl)amino)-2-oxoethyl)thio)pyridazin-3-yl)benzamide (CAS 1021060-86-5)
- Flecainide Impurity 5 (CAS CATO-C4X-25465)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
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