2-Acetamido-3-(3,4-dimethoxyphenyl)acrylic acid CAS 75649-49-9
| CAS No. | 75649-49-9 |
| Molecular Formula | C13H15NO5 |
| Molecular Weight | 265.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Acetamido-3-(3,4-dimethoxyphenyl)acrylic acid.
2-Acetamido-3-(3,4-dimethoxyphenyl)acrylic acid (CAS 75649-49-9), molecular formula C13H15NO5 and molecular weight 265.26 g/mol, is a CATO reference standard with documented purity and traceability.
2-Acetamido-3-(3,4-dimethoxyphenyl)acrylic acid (C13H15NO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H15NO5 |
| Molecular Weight | 265.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 1 |
Related Acetamido Standards
- 2-Acetamido-4-(benzyloxy)-4-oxobutanoic acid (CAS 10144-33-9)
- (S)-2-acetamido-3-(4-isopropoxyphenyl)propanoic acid (CAS 92501-74-1)
- Ethyl 2-Acetamido-2-deoxy-b-D-thioglucopyranoside (CAS 122331-70-8)
- Ethyl 2-acetamido-2-deoxy-β-D-thiogalactopyranoside (CAS 95074-13-8)
- Acetamido-5-benzylthio-1,3,4-thiadiazole (CAS 64387-67-3)
- 4-Acetamido-2-fluoro-5-methylbenzenesulfonyl chloride (CAS 71245-49-3)
- 4-Acetamido-6-methoxypyridine-2-sulfonyl chloride (CAS 1393545-10-2)
- 4-Acetamido-8-chloroquinoline-3-carboxylic acid (CAS 1352507-70-0)
Recommended Standards
- 2-{[(2,4-difluorophenyl)amino]methyl}-6-methoxyphenol (CAS 451469-51-5)
- 2-Acetoxy-3-cyanobenzophenone (CAS 890099-31-7)
- 2-[(Cyclopropylcarbonyl)amino]-4,5-dimethoxybenzoic Acid (CAS 496913-51-0)
- 2-Acetoxy-4-cyanobenzophenone (CAS 890099-34-0)
- N-((benzyloxy)carbonyl)-N-methylphenylalanine (CAS 81134-79-4)
- NI-57 (CAS 1883548-89-7)
- (2-(2-(Diethylamino)pyridin-3-yl)pyrrolidin-1-yl)(phenyl)methanone (CAS 1352484-71-9)
- (±)-MDEA-d5 hydrochloride (Ethyl-d5) (CAS 1286588-92-8)
- (3-Methylbutan-2-yl)(2-phenylethyl)amine (CAS 160254-20-6)
- 3-(1-Methylcyclopropyl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 1860179-53-8)
- (4R,5R)-5-(4-Iodophenyl)-2-phenyl-4,5-dihydrooxazole-4-methanol (CAS 927689-68-7)
- 3-[4-(Trifluoromethyl)phenoxy]propanoic acid (CAS 537013-50-6)
- 8-Fluoro-4-phenyl-2,3,3a,4,5,9b-hexahydro-furo[3,2-c]quinoline (CAS 937169-37-4)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com