N-(3,5-Dimethoxyphenyl)-2-(methylthio)nicotinamide CAS 756849-83-9
| CAS No. | 756849-83-9 |
| Molecular Formula | C15H16N2O3S |
| Molecular Weight | 304.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3,5-Dimethoxyphenyl)-2-(methylthio)nicotinamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(3,5-Dimethoxyphenyl)-2-(methylthio)nicotinamide (CAS 756849-83-9), molecular formula C15H16N2O3S and molecular weight 304.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3,5-Dimethoxyphenyl)-2-(methylthio)nicotinamide (C15H16N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(3,5-Dimethoxyphenyl)-2-(methylthio)nicotinamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H16N2O3S |
| Molecular Weight | 304.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-((2,5-Dimethoxyphenyl)thio)-6-methoxybenzaldehyde (CAS 1147093-19-3)
- N-(2,4-Dimethoxyphenyl)-2-(methylthio)nicotinamide (CAS 808792-10-1)
- N-(2,5-dimethoxyphenyl)-2-(pyridin-2-ylthio)acetamide (CAS 444165-07-5)
- N-(3,4-Dimethoxyphenyl)-2-(methylthio)nicotinamide (CAS 765285-31-2)
- 1-(2,5-Dimethoxyphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1416342-33-0)
- 3-(3,4-Dimethoxyphenyl)-3-(4-fluorophenyl)propanoic acid (CAS 1226051-86-0)
- 3-[3-(2,5-Dimethoxyphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]propanoic acid (CAS 1225973-06-7)
- 2-(3,4-Dimethoxyphenyl)-2-oxoethyl 5-methylfuran-2-carboxylate (CAS 749868-60-8)
Recommended Standards
- N-(4-(N-(m-Tolyl)sulfamoyl)phenyl)acetamide (CAS 289061-19-4)
- N-(3-(Methylcarbamoyl)-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)furan-2-carboxamide (CAS 892978-23-3)
- N-(4-(N-(o-Tolyl)sulfamoyl)phenyl)acetamide (CAS 19838-02-9)
- n-(4-Amino-2-methylphenyl)-3-methanesulfonylbenzamide (CAS 926215-09-0)
- 3-Bromo-5,6,7,8,9,10-hexahydroimidazo[1,2-a]azocine (CAS 1287217-31-5)
- T40U11PG20 67254-28-8 1,2-Dioleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt UNII-T40U11PG20 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (Sodium salt) 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), sodium salt 9-Octadecenoic acid (9Z)-, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1) DOPG Na, l- DOPG Na, r- DOPG-Na, l- DOPG-Na, r- (CAS 67254-28-8)
- 478039-81-5 6-methyl[1,2,4]triazolo[4,3-b]pyridazin-8-yl 3-(trifluoromethyl)benzenecarboxylate KS-00001VRV (CAS 478039-81-5)
- 3-{[3-(trifluoromethyl)phenyl]amino}propanenitrile (CAS 124438-60-4)
- 4-Amino-2-methyl-1,2-dihydroisoquinolin-3(4H)-one (CAS 209983-88-0)
- N-[(E)-1H-indol-3-ylmethylidene]-4H-1,2,4-triazol-4-amine (CAS 35554-74-6)
- 1-(2-Methoxybenzo[d]oxazol-4-yl)ethanone (CAS 1804035-36-6)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(acetamidothio)-3-methylbutanoic acid (CAS 1246647-73-3)
- 5-(1-Chloro-2-methylpropan-2-yl)-N-methyl-1,3,4-thiadiazol-2-amine (CAS 55391-19-0)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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