6-Chloro-5-methoxy-3-pyridinesulfonyl chloride CAS 75720-93-3
| CAS No. | 75720-93-3 |
| Molecular Formula | C6H5Cl2NO3S |
| Molecular Weight | 242.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Chloro-5-methoxy-3-pyridinesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Chloro-5-methoxy-3-pyridinesulfonyl chloride (CAS 75720-93-3), molecular formula C6H5Cl2NO3S and molecular weight 242.08 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-5-methoxy-3-pyridinesulfonyl chloride (C6H5Cl2NO3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H5Cl2NO3S |
| Molecular Weight | 242.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-methoxypyridine-3-sulfonyl chloride (CAS 1208081-26-8)
- 2-Chloro-6-methoxypyridine-4-sulfonyl chloride (CAS 1261468-23-8)
- 6-chloro-2-methoxypyridine-3-sulfonyl chloride (CAS 1261663-47-1)
- 5-chloro-6-methoxypyridine-3-sulfonyl chloride (CAS 1261785-22-1)
- 5-chloro-3-(4-chlorophenyl)-2-fluoropyridine (CAS 1364677-73-5)
- 6-Chloro-4-methoxypyridine-2-sulfonyl chloride (CAS 1393530-75-0)
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- 4-(sec-Butoxy)-3-iodobenzoic acid (CAS 1131614-17-9)
- 5-Cyclopropylspiro[indoline-3,4'-piperidin]-2-one (CAS 2416309-62-9)
- 4-Amino-2-(difluoromethyl)-5-iodopyridine-3-sulfonamide (CAS 1806795-38-9)
- 3,5-dimethyl-1-propyl-1H-pyrazol-4-amine,2HCl (CAS 1431966-81-2)
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