1-Mercapto-4-(2-methoxy-5-methylphenyl)-[1,2,4]triazolo[4,3-a]quinazolin-5(4h)-one CAS 757221-87-7
| CAS No. | 757221-87-7 |
| Molecular Formula | C17H14N4O2S |
| Molecular Weight | 338.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-Mercapto-4-(2-methoxy-5-methylphenyl)-[1,2,4]triazolo[4,3-a]quinazolin-5(4h)-one (CAS 757221-87-7), molecular formula C17H14N4O2S and molecular weight 338.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Mercapto-4-(2-methoxy-5-methylphenyl)-[1,2,4]triazolo[4,3-a]quinazolin-5(4h)-one (C17H14N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 1-Mercapto-4-(2-methoxy-5-methylphenyl)-[1,2,4]triazolo[4,3-a]quinazolin-5(4h)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14N4O2S |
| Molecular Weight | 338.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Ethyl 2-methyl-3-oxo-2,3-dihydropyridazine-4-carboxylate (CAS 1823900-71-5)
- (6-Chloroquinolin-4-yl)boronic acid (CAS 1312794-10-7)
- Ethyl 4-(3-(5-methyl-2-oxo-2,3-dihydro-1H-imidazol-4-yl)-5,6-dihydroimidazo[2,1-b]thiazol-2-yl)butanoate hydrobromide (CAS 1217173-45-9)
- 2-Bromo-4-chloro-6-(trifluoromethyl)aniline (CAS 912617-74-4)
- 2-(2,6-Dichloro-4-pyridyl)-2-propanol (CAS 95037-35-7)
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- 2-(3-Chlorophenyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid (CAS 2416673-66-8)
- Nicorandil Impurity 32 (CAS CATO-C4X-190732)
- 3-Methylisoxazole (CAS 30842-90-1)
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