(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)(2-(methylthio)pyridin-3-yl)methanone CAS 757227-12-6
| CAS No. | 757227-12-6 |
| Molecular Formula | C18H20ClN3OS |
| Molecular Weight | 361.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (4-(5-Chloro-2-methylphenyl)piperazin-1-yl)(2-(methylthio)pyridin-3-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies (4-(5-Chloro-2-methylphenyl)piperazin-1-yl)(2-(methylthio)pyridin-3-yl)methanone (CAS 757227-12-6), a certified reference material (molecular formula C18H20ClN3OS, MW 361.89 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, (4-(5-Chloro-2-methylphenyl)piperazin-1-yl)(2-(methylthio)pyridin-3-yl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 361.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H20ClN3OS |
| Molecular Weight | 361.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-(methylthio)-N-(5-(propylthio)-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide (CAS 833434-85-8)
- 3-Butyl-1-chloro-5,10-dihydro-8-(2-cyanophenyl)imidazol-[1,5-b]isoquinoline (CAS 1246814-77-6)
- 2-Chloro-N-((5-(thiophene-2-carbonyl)thiophen-2-yl)methyl)benzamide (CAS 1421528-09-7)
- 2-(4-(2-Chloro-6-fluorobenzyl)piperazin-1-yl)benzo[d]thiazole (CAS 478077-01-9)
- 4-(3-Chloro-4-methylphenyl)-5-((4-methoxyphenoxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 723332-63-6)
- 7-Chloro-1-[2-(ethylamino)ethyl]-5-(2-fluorophenyl)-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one (CAS 100234-77-3)
- 4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide (CAS 301676-12-0)
- 7-Chloro-5-(2-(4-methoxyphenyl)-2-oxoethyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one (CAS 303987-54-4)
Recommended Standards
- tert-butyl N-(3-chloro-6-fluoro-9H-pyrido[2,3-b]indol-8-yl)-N-methyl-carbamate (CAS 2245358-13-6)
- (4-Chlorophenyl)(4-hydroxy-4-((phenylthio)methyl)piperidin-1-yl)methanone (CAS 478248-09-8)
- tert-butyl 2'-chloro-4'-oxo-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-carboxylate (CAS 1307248-46-9)
- 2-(4-Chlorophenyl)-3-[(4-methylphenyl)sulfanyl]quinoline (CAS 477867-86-0)
- Copper, (4-bromo-3-hydroxy-2-naphthoato)(5-iodo-8-quinolinolato)- (CAS 14040-01-8)
- 2-Bromo-6-Nitrobenzaldehyde (CAS 20357-21-5)
- 3-Allyl-1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid (CAS 1936583-41-3)
- 2-((4-(tert-Butyl)benzyl)thio)-3-(4-ethoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477318-98-2)
- (R)-tert-Butyl 2-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-7-azaspiro[3.5]nonane-7-carboxylate (CAS 1421270-73-6)
- (S)-2-(4-fluoro-3-methoxyphenyl)-2-(methylamino)ethan-1-ol (CAS 1213154-52-9)
- 1-(4-Bromophenethyl)-4-methylpiperazine (CAS 855894-11-0)
- Ethyl 2-((3-chlorophenyl)amino)-2-oxoacetate (CAS 17710-00-8)
- 2-Tert-butyl-4-[(4-methoxyphenyl)methylidene]-1,2,3,4-tetrahydroacridine-9-carboxylic acid (CAS 380573-76-2)
- Peptide T (CAS 106362-32-7)
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