2-Ethynyl-6-methylpyridin-3-amine CAS 757950-12-2
| CAS No. | 757950-12-2 |
| Molecular Formula | C8H8N2 |
| Molecular Weight | 132.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Ethynyl-6-methylpyridin-3-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Ethynyl-6-methylpyridin-3-amine (CAS 757950-12-2), a certified reference material (molecular formula C8H8N2, MW 132.16 g/mol) for analytical method development and quality control.
The molecular framework of 2-Ethynyl-6-methylpyridin-3-amine (C8H8N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8N2 |
| Molecular Weight | 132.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Ethynyl Standards
- 5-Ethynyl-N-methylpyridin-2-amine (CAS 1056186-07-2)
- 5-Ethynyl-2-methylpyridin-3-amine (CAS 1211537-42-6)
- 2-Ethynyl-3,5-dimethylpyrazine (CAS 1374115-63-5)
- 2-Ethynyl-5-methylpyridin-3-amine (CAS 1394319-72-2)
- 2-Ethynyl-N-methylpyridin-4-amine (CAS 1565430-52-5)
- 6-Ethynyl-4-methylpyridin-2-amine (CAS 1582754-31-1)
- 5-Ethynyl-4-methylpyridin-2-amine (CAS 179555-05-6)
- 2-Ethynyl-5-methylphenol (CAS 1822650-88-3)
Recommended Standards
- 2-Ethynyl-6-methylphenol (CAS 99299-72-6)
- 2H-chromene (CAS 254-04-6)
- 2-Ethynyl-4,6-dimethylpyrimidine (CAS 86520-99-2)
- 2H-Cyclohepta[b]furan (CAS 275-76-3)
- 4-(Hexyloxy)phenyl 4-butylbenzoate (CAS 38454-28-3)
- 2-(Bromomethyl)-5-(difluoromethyl)-3-hydroxypyridine-4-methanol (CAS 1805533-91-8)
- (S)-pyrrolidin-2-ylmethyl acetate hydrochloride (CAS 635750-96-8)
- Methyl 8-methyl-1,2,3,4-tetrahydroquinoline-5-carboxylate (CAS 1030848-28-2)
- 1-Isopropylpyrazole-5-boronic Acid Pinacol Ester (CAS 1282518-60-8)
- 4-Chloro-N-(2,4-dimethylphenyl)benzamide (CAS 127292-01-7)
- 2-Chloro-N-(4-(N-isopropylsulfamoyl)phenyl)propanamide (CAS 790681-96-8)
- 6-Bromo-5-fluoro-1,3-benzoxazol-2-amine (CAS 1820740-13-3)
- 4-((2,2,2-Trifluoroethyl)thio)aniline (CAS 57946-59-5)
- Acetyl decapeptide-3 (CAS 935288-50-9)
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