1-(2-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile CAS 75838-07-2
| CAS No. | 75838-07-2 |
| Molecular Formula | C11H6ClN3O2 |
| Molecular Weight | 247.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile.
CATO supplies 1-(2-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 75838-07-2), a certified reference material (molecular formula C11H6ClN3O2, MW 247.64 g/mol) for analytical method development and quality control.
Structurally, 1-(2-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (C11H6ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 247.64 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6ClN3O2 |
| Molecular Weight | 247.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-3,6-dihydro-7h-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 114205-03-7)
- 3-(3-Chlorophenyl)-3,6-dihydro-7h-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 114205-04-8)
- 3-(4-Chlorophenyl)isoxazolo[5,4-d]pyrimidin-4(5H)-one (CAS 15783-73-0)
- 1-(4-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 75837-75-1)
- 1-(4-Chlorophenyl)-5-cyano-1H-pyrazole-4-carboxylic acid (CAS 98476-34-7)
- 2-((4-Chlorophenyl)ethynyl)-5-nitrofuran (CAS 58246-12-1)
- 3-(2-Chlorophenyl)-6-fluoro-[1,2,4]triazolo[4,3-a]pyridine (CAS 1443248-70-1)
- 2-((2-Chlorophenyl)amino)benzoic acid (CAS 10166-39-9)
Recommended Standards
- 3-Chlorobenzo[4,5]imidazo[1,2-a]pyrimidine-2-carboxylic acid (CAS 1956331-37-5)
- 4-(1H-1,2,3-benzotriazol-1-yl)-6-chloro-1,3,5-triazin-2-amine (CAS 1531560-72-1)
- 2-((6-Amino-3-chloro-5-nitropyrazin-2-yl)(methyl)amino)ethanol (CAS 88793-49-1)
- (R)-methyl 2-amino-3-(5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoate (CAS 1332725-55-9)
- 3-(tert-Butyl)-1-methyl-1H-pyrazol-5-amine (CAS 118430-73-2)
- (5-(2-Methoxyphenyl)-1H-imidazol-2-yl)methanamine (CAS 1156711-79-3)
- 6-(2-thiazol-2-ylethynyl)-1,2-benzoxazol-3-one (CAS 2570727-85-2)
- (2-(Piperazin-1-yl)pyridin-3-yl)(pyrrolidin-1-yl)methanone (CAS 902836-06-0)
- Tert-butyl 2-(((2-methoxyethyl)amino)methyl)piperidine-1-carboxylate (CAS 887588-49-0)
- 2-Cyanophenyl cyclobutyl ketone (CAS 898790-46-0)
- 5-[(4-bromo-1H-pyrazol-1-yl)methyl]-2-methylfuran-3-carboxylic acid (CAS 1179844-18-8)
- 2-(3-fluorooxetan-3-yl)ethan-1-ol (CAS 1123786-79-7)
- Ethyl 5-amino-1-(2-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylate (CAS 866838-05-3)
- T-Peptide (CAS 2022956-62-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com