2,3-Difluorobenzyl Alcohol CAS 75853-18-8
| CAS No. | 75853-18-8 |
| Molecular Formula | C7H6F2O |
| Molecular Weight | 144.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,3-Difluorobenzyl Alcohol (CAS 75853-18-8) is a high-purity analytical reference standard with the molecular formula C7H6F2O and a molecular weight of 144.12 g/mol.
The molecular framework of 2,3-Difluorobenzyl Alcohol (C7H6F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6F2O |
| Molecular Weight | 144.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
Related Difluorobenzyl Standards
- 3,4-Difluorobenzyl Alcohol (CAS 85118-05-4)
- 3,5-Difluorobenzyl alcohol (CAS 79538-20-8)
- 2,6-Difluorobenzyl Alcohol (CAS 19064-18-7)
- (2,5-difluorobenzyl)(2-methoxy-1-methylethyl)amine 4744-94-9 (CAS 4744-94-9)
- (2,6-Difluorobenzyl)hydrazine (CAS 887595-42-8)
- (3,4-Difluorobenzyl)hydrazine (CAS 887595-36-0)
- (3,5-Difluorobenzyl)hydrazine (CAS 887595-39-3)
- o-(2,5-Difluorobenzyl)hydroxylamine (CAS 1388030-23-6)
Recommended Standards
- 2,3-Difluoro-5-methylphenol (CAS 886037-58-7)
- 2,4-Difluoro-1-methoxybenzene (CAS 452-10-8)
- 2,3-Difluoro-4-methylphenol (CAS 261763-45-5)
- 2,4-Difluoro-3-methylphenol (CAS 959091-59-9)
- Methylhydrazine Dihydrochloride (CAS 55330-60-4)
- tert-Butyl (S)-2-((1R,2S)-3-(benzyloxy)-1-hydroxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate (CAS 173653-47-9)
- 3-Ethyl-2-(6-(N-phenylacetamido)hexa-1,3,5-trien-1-yl)benzo[d]oxazol-3-ium iodide (CAS 24136-83-2)
- (4-Fluorophenyl)(pyridin-4-yl)methanol (CAS 65214-62-2)
- Suc-Ala-Val-Pro-Phe-pNA (CAS 95192-38-4)
- 3-Methyl-4-(2-methylpentylidene)-1H-pyrazol-5(4H)-one (CAS 834898-56-5)
- Pitavastatin Impurity N1 (CAS 147511-70-4)
- 2-Hydroxy-4-iodobenzoic acid (CAS 16870-28-3)
- Oseltamivir Impurity X VII (Mixture) (CAS CATO-C4X-1720194)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
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