2-Bromo-N-[2-[7-Chloro-5-(2-Fluorophenyl)-2-Oxo-3H-1,4-Benzodiazepin-1-Yl]Ethyl]Acetamide CAS 75887-99-9
| CAS No. | 75887-99-9 |
| Molecular Formula | C19H16BrClFN3O2 |
| Molecular Weight | 452.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-N-[2-[7-Chloro-5-(2-Fluorophenyl)-2-Oxo-3H-1,4-Benzodiazepin-1-Yl]Ethyl]Acetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Bromo-N-[2-[7-Chloro-5-(2-Fluorophenyl)-2-Oxo-3H-1,4-Benzodiazepin-1-Yl]Ethyl]Acetamide (CAS 75887-99-9), molecular formula C19H16BrClFN3O2 and molecular weight 452.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-N-[2-[7-Chloro-5-(2-Fluorophenyl)-2-Oxo-3H-1,4-Benzodiazepin-1-Yl]Ethyl]Acetamide (C19H16BrClFN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Bromo-N-[2-[7-Chloro-5-(2-Fluorophenyl)-2-Oxo-3H-1,4-Benzodiazepin-1-Yl]Ethyl]Acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16BrClFN3O2 |
| Molecular Weight | 452.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 1,1A,2,6b-tetrahydrocyclopropa[a]pyrrolizin-6b-ol (CAS 183154-63-4)
- Hydroxy[2-(hydroxy-κO)-4-hydroxybenzoato-κO]copper (CAS 69868-09-3)
- (2S,3S)-Ethyl 2-acetamido-3-methylpentanoate (CAS 4819-22-1)
- 1-((2-Bromo-4,5-difluorophenyl)sulfonyl)pyrrolidine (CAS 1229294-17-0)
- 4-Bromo-2,5-dimethylbenzonitrile (CAS 292037-85-5)
- 2-(2-Chloro-3-fluorophenyl)acetonitrile (CAS 874285-20-8)
- 4-Iodo-1-methoxy-2-nitrobenzene (CAS 52692-09-8)
- Salbutamol Sulfate EP Impurity L HCl (CAS 898542-81-9（free base）)
- Endo-Gly29-Tirzepatide (CAS CATO-CPTD788685)
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