Theophylline EP Impurity C CAS 7597-60-6
| CAS No. | 7597-60-6 |
| Molecular Formula | C7H10N4O3 |
| Molecular Weight | 198.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Theophylline EP Impurity C is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Theophylline EP Impurity C (CAS 7597-60-6), a pharmacopoeial impurity reference standard (molecular formula C7H10N4O3, MW 198.18 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Theophylline EP Impurity C (C7H10N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H10N4O3 |
| Molecular Weight | 198.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 4 |
Related Theophylline Standards
- Theophylline Impurity 3 (CAS 60797-68-4)
- Theophylline EP Impurity E (CAS 944-73-0)
- Theophylline Impurity 10 (CAS CATO-C4X-182310)
- Theophylline Impurity 4 (CAS CATO-C4X-18234)
- Theophylline impurity 6 (CAS CATO-C4X-18236)
- Theophylline-d6 (CAS 117490-39-8)
- Theophylline Impurity 12 (CAS CATO-C4X-182312)
- Theophylline Impurity 14 (CAS CATO-C4X-182314)
Recommended Standards
- Epinephrine /Adrenaline Impurity 135 (CAS CATO-C4X-1849135)
- Urapidil Impurity 95 (CAS CATO-C4X-192495)
- N-(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)formamide (CAS CATO-C4X-244011)
- Norepinephrine Impurity 162 (CAS CATO-C4X-1514162)
- Tegoprazan impurity 83 (CAS CATO-C4X-229783)
- Edaravone impurity 55 (CAS CATO-C4X-106255)
- Empagliflozin impurity 317 (CAS CATO-C4X-1065317)
- 2,2-Difluoro-1-(5-Methyl-2-Furyl)-2-(Methylsulfanyl)Ethanone (CAS 170654-37-2)
- N-(4-formyl-1,3-thiazol-2-yl)-N-[4-(trifluoromethyl)phenyl]acetamide (CAS 1197825-54-9)
- Fleroxacin-D3 hydrochloride (CAS CATO-CCAD301428)
- Dexamethasone Impurity 95 (CAS CATO-C4X-116595)
- Nimodipine Metabolite 1 (CAS 85677-99-2)
- 4-Amino-5-methylimidazole Dihydrochloride (CAS 79681-02-0)
- Cholecystokinin Octapeptide (desulfated) (CAS 25679-24-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com