L-Leucine hydrochloride CAS 760-84-9
| CAS No. | 760-84-9 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of L-Leucine hydrochloride is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
L-Leucine hydrochloride (CAS 760-84-9), molecular formula C6H13NO2HCl and molecular weight 167.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of L-Leucine hydrochloride (C6H13NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H13NO2 HCl |
| Molecular Weight | 167.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related L Standards
- L-Leucine cyclopentyl ester hydrochloride (CAS 1018674-12-8)
- L-Leucine-d10 (CAS 106972-44-5)
- L-Leucine-13C6, D10 (CAS 1217445-25-4)
- L-leucine, 4-fluoro-, ethyl ester-4h2so4py (CAS 1459196-65-6)
- L-Leucine, N-(1-oxobutyl)-, 2,5-dioxo-1-pyrrolidinyl ester (CAS 1604040-21-2)
- D-Leucine Benzyl Ester p-Methylbenzenesulfonate (CAS 17664-93-6)
- L-Leucine 9-fluorenylmethyl ester hydrochloride (CAS 197162-68-8)
- L-Leucine, L-norvalyl- (CAS 200618-44-6)
Recommended Standards
- Tert-butyl ((S)-2-(4-nitrophenyl)-1-((R)-oxiran-2-yl)ethyl)carbamate (CAS 1352630-50-2)
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- 5-Amino-3-(tert-butyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 2411097-47-5)
- Crotonyl Coenzyme A (CAS 992-67-6)
- (S)-(1-(1-Aminoethyl)cyclohexyl)methanol (CAS 2380460-18-2)
- 4-Iodo-5-methyl-N-(1-methyl-1H-pyrazol-5-yl)pyridin-2-amine (CAS 2103386-67-8)
- N-(3,4-difluorophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide (CAS 303091-72-7)
- 5-(4-Bromophenyl)-3-phenylisoxazole (CAS 53573-22-1)
- 2-Methyl-4,5,6,7-tetrahydro-2H-indazol-3-amine (CAS 26503-23-1)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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