2-(3,4-Difluorophenyl)-2-methyl-1,3-dioxolane CAS 760211-65-2
| CAS No. | 760211-65-2 |
| Molecular Formula | C10H10F2O2 |
| Molecular Weight | 200.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(3,4-Difluorophenyl)-2-methyl-1,3-dioxolane (CAS 760211-65-2) is a high-purity analytical reference standard with the molecular formula C10H10F2O2 and a molecular weight of 200.18 g/mol.
The molecular framework of 2-(3,4-Difluorophenyl)-2-methyl-1,3-dioxolane (C10H10F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-(3,4-Difluorophenyl)-2-methyl-1,3-dioxolane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10F2O2 |
| Molecular Weight | 200.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Difluorophenyl Standards
- 2-(2,3-Difluorophenyl)-2-methylpropanoic acid (CAS 1035261-36-9)
- 3-(3,4-Difluorophenyl)butanoic acid (CAS 1042641-92-8)
- 3-(2,4-Difluorophenyl)butanoic acid (CAS 1042815-69-9)
- 4-(2,4-Difluorophenyl)butanoic acid (CAS 110931-78-7)
- 2-(2,6-Difluorophenyl)-2-methylpropanoic acid (CAS 1216838-87-7)
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- 2-(3,4-Difluorophenyl)butanoic acid (CAS 1226167-09-4)
- Methyl 2-(3,5-difluorophenyl)propanoate (CAS 1248159-75-2)
Recommended Standards
- 2-(3,4-Difluorobenzyl)-1,3-dioxolane (CAS 760211-54-9)
- 2-(3,4-Difluorophenyl)-2-methylpropanoic acid (CAS 306761-55-7)
- 2-(2,6-Difluorophenyl)butanoic acid (CAS 359828-70-9)
- 2-(3,5-Difluorophenyl)-2-methylpropanoic acid (CAS 879904-44-6)
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