2-(1,2,3,4-Tetrahydroquinolin-4-yl)acetic acid CAS 76059-57-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1,2,3,4-Tetrahydroquinolin-4-yl)acetic acid.

2-(1,2,3,4-Tetrahydroquinolin-4-yl)acetic acid (CAS 76059-57-9) is a high-purity analytical reference standard with the molecular formula C11H13NO2 and a molecular weight of 191.23 g/mol.

2-(1,2,3,4-Tetrahydroquinolin-4-yl)acetic acid (C11H13NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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