2-Bromo-3-methoxy-6-nitropyridine CAS 76066-07-4
| CAS No. | 76066-07-4 |
| Molecular Formula | C6H5BrN2O3 |
| Molecular Weight | 233.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Bromo-3-methoxy-6-nitropyridine (CAS 76066-07-4) is a high-purity analytical reference standard with the molecular formula C6H5BrN2O3 and a molecular weight of 233.02 g/mol.
The molecular framework of 2-Bromo-3-methoxy-6-nitropyridine (C6H5BrN2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Bromo-3-methoxy-6-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BrN2O3 |
| Molecular Weight | 233.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- Methyl 5-bromo-2-formylfuran-3-carboxylate (CAS 1006598-64-6)
- 4-Bromo-6-methyl-2-nitropyridin-3-ol (CAS 1022250-67-4)
- 2-Bromo-4,6-dihydroxybenzoic acid (CAS 1037751-00-0)
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- 2-Bromo-3-methoxy-5-nitropyridine (CAS 1353101-84-4)
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Recommended Standards
- 2-Amino-5-bromo-3-nitrophenol (CAS 867338-56-5)
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- 2-Bromo-5-methyl-4-nitropyridin-3-ol (CAS 2869955-53-1)
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- 8-Ethyl-2-pyridin-2-ylquinoline-4-carbonylchloride hydrochloride (CAS 1332530-99-0)
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- 2-Fluoro-6-methoxybenzaldehyde (CAS 146137-74-8)
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- 1-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-methyl-1H-pyrazol-5-amine (CAS 1415719-61-7)
- 5-(1-Methylcyclopropyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 436088-54-9)
- Methyl 2-hydroxyhex-5-ynoate (CAS 1490824-17-3)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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