4-(5-Chlorothiophen-2-yl)-1h-pyrazole CAS 76153-69-0
| CAS No. | 76153-69-0 |
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(5-Chlorothiophen-2-yl)-1h-pyrazole (CAS 76153-69-0) is a high-purity analytical reference standard with the molecular formula C7H5ClN2S and a molecular weight of 184.65 g/mol.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system, 4-(5-Chlorothiophen-2-yl)-1h-pyrazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorothiophen Standards
- 3-(3-Chlorothiophen-2-yl)-1H-pyrazole (CAS 166196-59-4)
- 3-(5-Chlorothiophen-2-yl)-1H-pyrazole (CAS 166196-61-8)
- 3-(5-Chlorothiophen-2-yl)-3-oxopropanenitrile (CAS 71683-01-7)
- 3-(4-Chlorothiophen-2-yl)propiolic acid (CAS 1403566-51-7)
- 3-(5-Chlorothiophen-2-yl)propiolic acid (CAS 874513-01-6)
- 5-(5-Chlorothiophen-2-yl)-2H-tetrazole (CAS 58884-89-2)
- 4-(4-Chlorothiophen-2-yl)but-3-en-2-one (CAS 1563844-27-8)
- 3-(5-Chlorothiophen-2-yl)-2-methylprop-2-enal (CAS 1563958-97-3)
Recommended Standards
- 2-Chlorothieno[3,2-b]pyridin-3-amine (CAS 26579-61-3)
- 4-Amino-2-chlorophenyl thiocyanate (CAS 3226-46-8)
- 2-Chlorobenzo[d]thiazol-6-amine (CAS 2406-90-8)
- 4-Chloro-1H-benzo[d]imidazole-2(3H)-thione (CAS 75335-72-7)
- Ethyl 4-propionylbenzoate (CAS 860344-87-2)
- 2-Morpholino-N-phenethylethan-1-amine (CAS 312927-61-0)
- N-(4-Amino-2-methyl-6-quinolinyl)acetamide (CAS 63304-46-1)
- 4-Fluorobenzo[d]thiazol-7-amine (CAS 1807013-58-6)
- 7-Fluoro-3H-imidazo[4,5-b]pyridine (CAS 1305207-46-8)
- 5-ethoxypyrazine-2-carboxylic acid (CAS 1220330-11-9)
- 1-(3-(Methylthio)phenyl)but-3-en-1-ol (CAS 1378462-37-3)
- 3-methyl-N-(pentan-3-yl)aniline (CAS 1019587-47-3)
- Baloxavir Impurity 103 (CAS 2762066-96-4)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com